Klein R S, Warman S W, Knackmuhs G G, Edberg S C, Steigbigel N H
Am J Gastroenterol. 1987 Jun;82(6):540-3.
Since previous studies have shown an increased fecal carriage rate of Streptococcus bovis in patients with carcinoma of the colon, a study was undertaken to determine the fecal carriage rate of this organism in patients with gastrointestinal carcinoma of noncolonic origin. Organisms identified as S. bovis were isolated on fecal culture from 10 of 82 (12%) controls, 19 of 94 (20%) individuals with noncolonic gastrointestinal carcinoma, and 12 of 80 (15%) patients with other gastrointestinal disorders. Subjects with noncolonic gastrointestinal carcinoma did not have a fecal carriage rate of S. bovis significantly different from that in controls. A literature review of 251 patients with S. bovis septicemia identified at least 89 (35%) with neoplasms of the colon. Only nine patients (4%) with gastrointestinal neoplasms of other than colonic origin were noted. At present, the indication for an intensive evaluation of the upper gastrointestinal tract in individuals with S. bovis bacteremia is substantially less than that for the colon.
由于先前的研究表明，结肠癌患者中牛链球菌的粪便携带率有所增加，因此开展了一项研究，以确定非结肠来源的胃肠道癌患者中该菌的粪便携带率。在粪便培养中，从82名对照者中的10名（12%）、94名非结肠胃肠道癌患者中的19名（20%）以及80名其他胃肠道疾病患者中的12名（15%）分离出被鉴定为牛链球菌的菌株。非结肠胃肠道癌患者的牛链球菌粪便携带率与对照者相比无显著差异。对251例牛链球菌败血症患者的文献综述发现，至少89例（35%）患有结肠癌。仅发现9例（4%）患有非结肠来源的胃肠道肿瘤。目前，对牛链球菌菌血症患者进行上消化道强化评估的指征远低于对结肠的评估指征。
