Wissel P S, Sordillo P, Anderson K E, Sassa S, Savillo R L, Kappas A
Am J Hematol. 1987 May;25(1):107-13. doi: 10.1002/ajh.2830250112.
Three male subjects with cutaneous symptoms and biochemical signs typical of porphyria cutanea tarda (PCT) developed acquired immune deficiency syndrome (AIDS). All three were in a classic high risk group for the latter disease and developed a typical progressive illness. Two patients succumbed to opportunistic infections; the third is alive but critically ill. The symptomatic prodrome of AIDS developed concurrently with or followed the onset of symptoms of PCT in all three individuals. PCT and AIDS are both uncommon disorders; their association in three patients is thus of inherent clinical interest. If this association is not coincidental, it raises the possibility that the occurrence of photosensitivity, skin lesions, and evidence of biochemical changes characteristic of PCT may, in certain patients at risk for AIDS, presage the subsequent full clinical expression of the latter disease.
三名患有迟发性皮肤卟啉症（PCT）典型皮肤症状和生化体征的男性受试者患上了获得性免疫缺陷综合征（AIDS）。这三人都属于后一种疾病的典型高危人群，并患上了典型的进行性疾病。两名患者死于机会性感染；第三名患者存活但病情危急。在所有三名患者中，AIDS的症状前驱期与PCT症状的出现同时发生或在其之后出现。PCT和AIDS都是不常见的疾病；因此，它们在三名患者中的关联具有内在的临床意义。如果这种关联不是巧合，那么就增加了一种可能性，即在某些有AIDS风险的患者中，PCT特征性的光敏性、皮肤病变和生化变化证据可能预示着后一种疾病随后的全面临床表现。
