阿片类物质使用障碍药物治疗患者中芬太尼检测试纸的使用情况及过量用药史
Fentanyl Test Strip Use and Overdose History among Individuals on Medication for Opioid Use Disorder.
作者信息
Mistler C B, Rosen A O, Eger W, Copenhaver M M, Shrestha R
机构信息
Department of Allied Health Sciences, University of Connecticut, Storrs, CT, USA.
Institute for Collaboration on Health, Intervention and Policy (InCHIP), University of Connecticut, Storrs, CT, USA.
出版信息
Austin J Public Health Epidemiol. 2021;8(5). Epub 2021 Dec 29.
BACKGROUND
The number of deaths from drug overdose in the United States has more than doubled in the past decade. In particular, drug overdose deaths involving fentanyl have doubled every year since 2013. Rapid fentanyl test strips (FTS) are a useful strategy for detecting traces of fentanyl in substances and have received overwhelming support from individuals with opioid-dependence.
METHODS
We investigated fentanyl use, knowledge of FTS, willingness to use FTS, and overdose history among a sample of 105 individuals currently on medication for opioid use disorder (MOUD).
RESULTS
Results showed that the majority (63%) of the sample had experienced a non-fatal overdose and that 85% of participants were willing to use FTS. The majority of participants reported concern about fentanyl in their drug supply (70%) and 77% reported likelihood of past unintentional fentanyl use. Of note, only about half (47%) of participants knew of FTS prior to being surveyed, and only 17% reported ever using FTS.
CONCLUSION
These results expand on previous literature that documents high levels of willingness, yet low uptake of FTS among individuals on MOUD. Widespread education about FTS, in addition to the implementation of the use of FTS, is a highly promising and critical primary prevention alternative to overdose treatment and/or death due to fentanyl.
背景
在过去十年中，美国药物过量致死人数增加了一倍多。特别是，自2013年以来，涉及芬太尼的药物过量死亡人数每年都翻一番。快速芬太尼检测试纸（FTS）是检测物质中芬太尼痕迹的一种有用策略，并得到了阿片类药物依赖者的大力支持。
方法
我们调查了105名目前正在接受阿片类药物使用障碍（MOUD）药物治疗的个体样本中的芬太尼使用情况、对FTS的了解程度、使用FTS的意愿以及过量用药史。
结果
结果显示，大多数（63%）样本经历过非致命性过量用药，85%的参与者愿意使用FTS。大多数参与者表示担心其毒品供应中有芬太尼（70%），77%的参与者报告过去有意外使用芬太尼的可能性。值得注意的是，在接受调查之前，只有约一半（47%）的参与者知道FTS，只有17%的参与者报告曾使用过FTS。
结论
这些结果扩展了先前的文献，这些文献记录了MOUD患者对FTS的高意愿度，但使用率较低。除了推广使用FTS之外，广泛开展关于FTS的教育是一种非常有前景且关键的初级预防措施，可替代因芬太尼导致的过量用药治疗和/或死亡。
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