Parks Olivia B, Keith Mary, Squires Judy H, Venkat Veena L, Mahmood Burhan
Medical Scientist Training Program, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Division of Newborn Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA.
ACG Case Rep J. 2022 Jul 1;9(7):e00817. doi: 10.14309/crj.0000000000000817. eCollection 2022 Jul.
Hepatic abscesses in premature infants are rare with less than 100 case reports documented in literature. We report a case of a premature infant diagnosed with hepatic microabscesses secondary to eosinophilic colitis. A 33 4/7-week preterm female neonate presented with bilious emesis, abdominal distention, and severe hematochezia. Eosinophilic enterocolitis was suspected. Hypoechoic regions in the anterior liver identified on computed tomography were considered liver microabscesses. This unique case exemplifies how prematurity increases the risk of mucosal damage in the presence of eosinophilic colitis causing enteric bacteria to seed into the liver through the portal vein, resulting in hepatic microabscesses.
早产儿肝脓肿较为罕见，文献记载的病例报告不足100例。我们报告一例早产儿诊断为嗜酸性粒细胞性结肠炎继发肝微脓肿。一名33又4/7周早产女婴出现胆汁性呕吐、腹胀和严重便血。怀疑为嗜酸性粒细胞性小肠结肠炎。计算机断层扫描发现肝脏前部的低回声区被认为是肝微脓肿。这个独特的病例说明了早产如何增加了嗜酸性粒细胞性结肠炎存在时黏膜损伤的风险，导致肠道细菌通过门静脉播散至肝脏，从而形成肝微脓肿。
