美国高血压伴治疗失眠患者的心脏事件和经济负担。

Cardiac events and economic burden among patients with hypertension and treated insomnia in the USA.

机构信息

Department of Psychiatry, University of Maryland, Baltimore, MD 21201, USA.

Sleep Disorders Center, Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Maryland, Baltimore, MD 21201, USA.

出版信息

Future Cardiol. 2022 Sep;18(9):731-741. doi: 10.2217/fca-2022-0009. Epub 2022 Jul 5.

DOI:10.2217/fca-2022-0009

PMID:35787013

Abstract

Cardiovascular (CV) event risk, healthcare resource utilization (HCRU) and costs have not been elucidated among hypertension patients with treated insomnia (H + TI). Adult patients with H + TI were identified in IBM MarketScan databases. H + TI patients were matched 1:1 on age and sex to controls with hypertension but without sleep disorders. Multivariable models were used to estimate associations between treated insomnia and CV event risk, HCRU and costs. In total, 81,502 H + TI patients (mean age = 62 years, 53% female) were matched. Relative to controls, H + TI patients were 2.4 times as likely to have CV events. H + TI patients incurred higher costs per patient per month (US$2343 vs US$1013). Treated insomnia was associated with higher costs and HRCU in hypertension patients.

摘要

在患有治疗失眠的高血压患者（H+TI）中，心血管（CV）事件风险、医疗资源利用（HCRU）和成本尚不清楚。在 IBM MarketScan 数据库中确定了患有 H+TI 的成年患者。将 H+TI 患者按年龄和性别与没有睡眠障碍的高血压但没有睡眠障碍的对照患者进行 1:1 匹配。使用多变量模型来估计治疗失眠与 CV 事件风险、HCRU 和成本之间的关联。共有 81,502 名 H+TI 患者（平均年龄 62 岁，53%为女性）进行了匹配。与对照组相比，H+TI 患者发生 CV 事件的可能性是对照组的 2.4 倍。H+TI 患者的每位患者每月的成本更高（2343 美元对 1013 美元）。治疗失眠与高血压患者的更高成本和 HRCU 相关。