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2002-2016 年基于瑞典全国患者登记系统的全国性研究:儿童桡骨远端骨折发病率和季节变化的长期趋势。

Secular trends in incidence and seasonal variation of distal radius fracture among children: A nationwide study based on the Swedish National Patient Register 2002-2016.

机构信息

Division of Orthopaedics and Biotechnology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden; Department of Orthopedic Surgery, Showa University School of Medicine, Tokyo, Japan.

Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.

出版信息

Bone. 2022 Sep;162:116479. doi: 10.1016/j.bone.2022.116479. Epub 2022 Jul 2.

Abstract

BACKGROUND AND PURPOSE

Although distal radius fracture (DRF) is the most common fracture type in children, research on its seasonality across different age groups is limited. We investigated secular trends in incidence and seasonal variation of pediatric DRF based on Swedish nationwide population database.

PATIENTS AND METHODS

In this observational study, data for all children aged <18 years in Sweden with DRF defined by ICD-codes were analyzed for each month and each year during 2002-2016 using the Swedish National Patient Register. The general population counts for each age and sex-category were acquired to evaluate population at risk for each period. We calculated the age standardized and sex specific annual incidence rates, seasonal incidence rates, and monthly incidence rates and analyzed the seasonal variation in the mechanisms of injury.

RESULTS

A total of 155,891 DRF cases were identified. The age standardized and sex specific incidence rate was 531 (95%CI 528-533) per 100,000 patient years at risk. Fracture risk was highest during summer and lowest in the winter. The highest seasonal variation was observed among boys 2- < 5 years. The crude incidence rate and the age-standardized incidence rates in winter significantly decreased between 2002 and 2016 (annual percentage change, -2 %).

INTERPRETATION

We found significant seasonal variation in DRF among all age groups in Swedish children. The findings can help in developing strategies to prevent fractures as well as in allocating medical and social resources.

摘要

背景与目的

尽管桡骨远端骨折(DRF)是儿童中最常见的骨折类型,但针对不同年龄组的其季节性变化的研究却很有限。我们基于瑞典全国人口数据库,研究了儿童 DRF 的发病率的季节性变化趋势。

患者与方法

在这项观察性研究中,我们分析了 2002 年至 2016 年期间瑞典所有年龄<18 岁且 ICD 编码为 DRF 的儿童的数据。使用瑞典全国患者登记处,按月份和年份分析了每个月和每年的病例。获取了每个年龄和性别类别的人群计数,以评估每个时期的风险人群。我们计算了年龄标准化和性别特异性的年发病率、季节性发病率、月发病率,并分析了损伤机制的季节性变化。

结果

共确定了 155891 例 DRF 病例。年龄标准化和性别特异性的发病率为每 100,000 人风险患者年 531 例(95%CI 528-533)。骨折风险在夏季最高,冬季最低。2-<5 岁男孩的季节性变化最大。2002 年至 2016 年期间,冬季的未校正发病率和年龄标准化发病率显著下降(年变化百分比,-2%)。

结论

我们发现瑞典儿童所有年龄组的 DRF 都存在明显的季节性变化。这些发现有助于制定预防骨折的策略,并分配医疗和社会资源。

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