Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia.
Heart Surg Forum. 2022 May 31;25(3):E425-E428. doi: 10.1532/hsf.4123.
This study aimed to compare postoperative ejection fraction (EF) in response to coronary artery bypass grafting (CABG) among patients with preoperative EF <35% and >35%.
A retrospective study was conducted in a single institution using clinical data of 660 patients undergoing elective on-pump CABG in 2018-2019. Patients were classified into two groups based on preoperative left ventricle ejection fraction (<35% and >35%). The primary endpoint was the change of postoperative ejection fraction.
In this study, 72 patients had preoperative left ventricle ejection fraction <35% (group A) while the other 588 patients had ejection fraction >35% (group B). Among both groups, the duration of cardiopulmonary bypass (CPB) and aortic clamp (AxC) were not significantly different (P > 0.05). The transformation of pre- and postoperative EF in groups A and B was significantly different (2.91+10.31 vs. -0.14+4.57, P < 0.001). There was a significant difference in the duration of ICU stay (73.42+112.55 vs. 34.43+64.99, P < 0.001) and postoperative ventilatory support (25.54+43.92 vs. 16.42+45.87, P < 0.008) between group A and B.
Low preoperative EF showed better improvement in cardiac function after surgery. We concluded that the result could be affected by revascularization of hibernating myocardium.
本研究旨在比较术前射血分数（EF）<35%和>35%的患者行冠状动脉旁路移植术（CABG）后的术后 EF 变化。
在 2018-2019 年，对在一家单中心接受体外循环 CABG 的 660 例择期手术患者的临床数据进行回顾性研究。根据术前左心室射血分数（<35%和>35%）将患者分为两组。主要终点是术后射血分数的变化。
在这项研究中，72 例患者术前左心室射血分数<35%（A 组），而其余 588 例患者射血分数>35%（B 组）。两组患者体外循环（CPB）和主动脉夹闭（AxC）时间无显著差异（P>0.05）。A 组和 B 组的术前和术后 EF 变化有显著差异（2.91+10.31 比-0.14+4.57，P<0.001）。A 组和 B 组的 ICU 停留时间（73.42+112.55 比 34.43+64.99，P<0.001）和术后通气支持时间（25.54+43.92 比 16.42+45.87，P<0.008）有显著差异。
术前 EF 较低的患者术后心功能改善更好。我们的结论是，这一结果可能受到冬眠心肌再血管化的影响。
