完全血运重建可改善射血分数较低患者的心脏功能。

Complete Revascularization Showed A Better Cardiac Function Improvement In Patients With Low Ejection Fraction.

机构信息

Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia.

出版信息

Heart Surg Forum. 2022 May 31;25(3):E425-E428. doi: 10.1532/hsf.4123.

DOI:10.1532/hsf.4123

PMID:35787771

Abstract

PURPOSE

This study aimed to compare postoperative ejection fraction (EF) in response to coronary artery bypass grafting (CABG) among patients with preoperative EF <35% and >35%.

METHODS

A retrospective study was conducted in a single institution using clinical data of 660 patients undergoing elective on-pump CABG in 2018-2019. Patients were classified into two groups based on preoperative left ventricle ejection fraction (<35% and >35%). The primary endpoint was the change of postoperative ejection fraction.

RESULTS

In this study, 72 patients had preoperative left ventricle ejection fraction <35% (group A) while the other 588 patients had ejection fraction >35% (group B). Among both groups, the duration of cardiopulmonary bypass (CPB) and aortic clamp (AxC) were not significantly different (P > 0.05). The transformation of pre- and postoperative EF in groups A and B was significantly different (2.91+10.31 vs. -0.14+4.57, P < 0.001). There was a significant difference in the duration of ICU stay (73.42+112.55 vs. 34.43+64.99, P < 0.001) and postoperative ventilatory support (25.54+43.92 vs. 16.42+45.87, P < 0.008) between group A and B.

CONCLUSION

Low preoperative EF showed better improvement in cardiac function after surgery. We concluded that the result could be affected by revascularization of hibernating myocardium.

摘要

目的

本研究旨在比较术前射血分数（EF）<35%和>35%的患者行冠状动脉旁路移植术（CABG）后的术后 EF 变化。

方法

在 2018-2019 年，对在一家单中心接受体外循环 CABG 的 660 例择期手术患者的临床数据进行回顾性研究。根据术前左心室射血分数（<35%和>35%）将患者分为两组。主要终点是术后射血分数的变化。

结果

在这项研究中，72 例患者术前左心室射血分数<35%（A 组），而其余 588 例患者射血分数>35%（B 组）。两组患者体外循环（CPB）和主动脉夹闭（AxC）时间无显著差异（P>0.05）。A 组和 B 组的术前和术后 EF 变化有显著差异（2.91+10.31 比-0.14+4.57，P<0.001）。A 组和 B 组的 ICU 停留时间（73.42+112.55 比 34.43+64.99，P<0.001）和术后通气支持时间（25.54+43.92 比 16.42+45.87，P<0.008）有显著差异。