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[用替吉兰诺酯成功局部治疗犬指部肥大细胞瘤]

[Successful local treatment of a digital canine mast cell tumour with Tigilanol Tiglate].

作者信息

Gasser Karin

机构信息

Tierklinik Schwarzmann Rankweil OG.

出版信息

Tierarztl Prax Ausg K Kleintiere Heimtiere. 2022 Jun;50(3):225-231. doi: 10.1055/a-1844-8554. Epub 2022 Jul 5.

DOI:10.1055/a-1844-8554
PMID:35790169
Abstract

Surgical excision is currently the recommended treatment for resectable, nonmetastatic mast cell tumours. Recently, Tigilanol tiglate has become available as a novel intratumoral treatment modality for a subset of cutaneous and subcutaneous mast cell tumours. In the presented case, we document the successful treatment of a 0.445 cm subcutaneous digital mast cell tumour in an American Staffordshire Terrier. The resulting wound healed completely and without complications within 4 weeks and the dog was recurrence-free 8 months after treatment. Due to this new intratumoral treatment it was possible to preserve the digit, while a complete surgical resection of the tumour would have required digital amputation.

摘要

手术切除目前是可切除的非转移性肥大细胞瘤的推荐治疗方法。最近,替吉兰醇替格列酯已成为一种新型的肿瘤内治疗方式,用于治疗一部分皮肤和皮下肥大细胞瘤。在本病例中,我们记录了一只美国斯塔福郡梗犬的0.445厘米皮下指部肥大细胞瘤的成功治疗。伤口在4周内完全愈合且无并发症,治疗后8个月该犬无复发。由于这种新的肿瘤内治疗方法,得以保留该指部,而若进行肿瘤的完整手术切除则需要进行指部截肢。

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