日本胃癌协会全国登记处（2001-2013 年）手术切除胃癌病例的回顾性 5 年生存分析。
A retrospective 5-year survival analysis of surgically resected gastric cancer cases from the Japanese Gastric Cancer Association nationwide registry (2001-2013).
机构信息
Division of Gastrointestinal Surgery, Department of Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.
Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata, Japan.
出版信息
Gastric Cancer. 2022 Nov;25(6):1082-1093. doi: 10.1007/s10120-022-01317-6. Epub 2022 Jul 5.
BACKGROUND
The nationwide registry of the Japanese Gastric Cancer Association collected data of surgically resected cases of gastric cancer between 2001 and 2013. These retrospective analyses aimed to delineate tumor characteristics, surgical history, and survival distribution.
METHODS
Data from 254,706 patients with primary gastric cancer were included. The 5-year survival rates were calculated for various subsets of prognostic factors.
RESULTS
The number of patients over 70 years old increased from 2001 to 2013. The frequency with which laparoscopic gastrectomy was opted for increased dramatically (from 3.5 to 40.8%) in 13 years. We focused on the patients registered between 2010 and 2013, for whom data collection was based on the 3rd edition of the Japanese classification and guidelines. Five-year overall survival (OS) rate among 92,305 patients with resected tumors was 70.6%. The 5-year OS rates of patients with pathological stage IA, IB, IIA, IIB, IIIA, IIIB, IIIC, and IV disease were 89.6%, 83.2%, 77.6%, 68.1%, 59.3%, 45.6%, 29.9%, and 14.0%, respectively.
CONCLUSION
Our detailed analysis highlights the historical changes in outcomes of surgically treated gastric malignancies in Japan, and provides robust dataset for future analysis.
背景
日本胃癌协会全国注册系统收集了 2001 年至 2013 年间手术切除的胃癌病例数据。这些回顾性分析旨在描述肿瘤特征、手术史和生存分布。
方法
纳入了 254706 例原发性胃癌患者的数据。对各种预后因素亚组计算了 5 年生存率。
结果
2001 年至 2013 年，70 岁以上患者的数量有所增加。腹腔镜胃切除术的选择频率在 13 年内从 3.5%急剧上升至 40.8%。我们专注于 2010 年至 2013 年期间登记的患者，这些患者的数据收集基于日本分类和指南的第 3 版。92305 例可切除肿瘤患者的 5 年总生存率（OS）为 70.6%。病理分期为 IA、IB、IIA、IIB、IIIA、IIIB、IIIC 和 IV 期的患者 5 年 OS 率分别为 89.6%、83.2%、77.6%、68.1%、59.3%、45.6%、29.9%和 14.0%。
结论
我们的详细分析突出了日本手术治疗胃癌结果的历史变化，并为未来的分析提供了可靠的数据集。
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