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髋关节疼痛与疑似中轴型脊柱关节炎患者的髋臼发育不良相关:DESIR 队列研究数据。

Hip Pain Associated with Acetabular Dysplasia in Patients with Suspected Axial Spondyloarthritis: DESIR Cohort Data.

机构信息

Service de rhumatologie, CHU Brest, INSERM CIC 1412, Brest, France.

Service de rhumatologie, Département de médecine du sport, CHU Brest, Brest, France.

出版信息

BMC Musculoskelet Disord. 2022 Jul 5;23(1):640. doi: 10.1186/s12891-022-05575-4.

Abstract

OBJECTIVES

To determine whether acetabular dysplasia is associated with hip pain at physical examination among adults with recent-onset inflammatory back pain (IBP) suggesting axial spondyloarthritis (axSpA).

METHODS

This cross-sectional ancillary study was conducted on the prospective DESIR cohort, which enrolled patients aged 18-50 years who had recent-onset IBP. Two readers used antero-posterior pelvic radiographs to assess the Tönnis angle, acetabular angle (AA), lateral centre-edge angle (LCEA), and femoral head extrusion index (FHEI). Abnormality of one or more of these four variables defined acetabular dysplasia. Hip pain upon physical examination was assessed based on Ritchie's articular index.

RESULTS

The overall prevalence of acetabular dysplasia was 22% (139/636). The proportion of females was higher in the group with acetabular dysplasia. Hip pain was found in 21% (29/139) of patients with versus 12% (59/497) without acetabular dysplasia (OR, 1.96; 95% CI, 1.20 to 3.20); the association was significant in males (OR, 3.14; 95% CI, 1.44 to 6.86) but not females (OR, 1.39; 95% CI, 0.74 to 2.62). Results were similar when acetabular dysplasia was defined on the basis of LCEA alone (OR, 2.15; 95% CI, 1.18 to 2.62).

CONCLUSION

Among patients with recent-onset IBP suggesting axSpA, acetabular dysplasia was significantly associated with hip pain in males. Hip pain related to acetabular dysplasia might result in overdiagnosis of hip involvement by axSpA.

摘要

目的

确定在提示存在中轴型脊柱关节炎(axSpA)的近期发作性炎症性背痛(IBP)成年患者中,髋臼发育不良是否与体格检查时的髋部疼痛相关。

方法

本横断面辅助研究纳入了前瞻性 DESIR 队列中的患者,这些患者年龄在 18-50 岁之间,近期发作 IBP。两位读者使用前后骨盆 X 线片评估 Tönnis 角、髋臼角(AA)、外侧中心边缘角(LCEA)和股骨头挤出指数(FHEI)。如果这四个变量中的一个或多个异常,则定义为髋臼发育不良。根据 Ritchie 关节指数评估体格检查时的髋部疼痛。

结果

髋臼发育不良的总体患病率为 22%(139/636)。髋臼发育不良组中女性的比例较高。在髋臼发育不良患者中,21%(29/139)的患者存在髋部疼痛,而在无髋臼发育不良患者中为 12%(59/497)(OR,1.96;95%CI,1.20 至 3.20);该关联在男性中具有统计学意义(OR,3.14;95%CI,1.44 至 6.86),但在女性中无统计学意义(OR,1.39;95%CI,0.74 至 2.62)。当仅根据 LCEA 定义髋臼发育不良时,结果相似(OR,2.15;95%CI,1.18 至 2.62)。

结论

在提示存在 axSpA 的近期发作性 IBP 患者中,髋臼发育不良与男性的髋部疼痛显著相关。与髋臼发育不良相关的髋部疼痛可能导致 axSpA 髋关节受累的过度诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7502/9254538/d42c4ddda049/12891_2022_5575_Fig1_HTML.jpg

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