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[短暂性妄想障碍与精神分裂症。两组患者的比较随访研究]

[Transient delusional disorders and schizophrenia. Comparative catamnestic study of 2 groups of patients].

作者信息

Singer L, Roos L, Danion J M, Heidet S

出版信息

Ann Med Psychol (Paris). 1986 Dec;144(10):1029-43.

PMID:3579104
Abstract

The authors investigated, in 1982, the situation of two groups of patients who had spent at least 8 days in the Psychiatric Clinic of the Strasbourg University Hospital in 1972, one group of whom had been diagnosed as suffering from "bouffée délirante aiguë" (B.D.A.), and another, from schizophrenia. In 1982, the former consisted of 43 people, 26 women and 17 men, and the latter of 72, 24 women and 48 men. The catamnesis was elaborated on the basis of social security files and information provided by physicians. All possible precautions were taken to protect professional secrecy and patients' anonymity. The data collected were subjectived to statistical analysis to establish correlations between certain variables and, on the basis of these variables, the traditional French classification was compared with that of the D.S.M. III. The outcome of patients suffering from B.D.A. was significantly better than those considered as schizophrenics. However, in 11 out of 26 patients with a B.D.A. diagnosis in 1972, there was an evolution towards schizophrenia, whereas 10 of the 44 schizophrenics displayed no handicap 10 years later. As regards the comparison between the prognostic values of the traditional French classification and D.S.M. III, the latter appeared more restrictive as to the diagnosis of schizophrenia with perhaps a clearer prognostic value. This catamnistic study further reinforces the arguments in favour of the existence of the B.D.A. as a clinical category. Further in-depth research in the genetic, biological and psychopathological fields should yield answers to the many questions still remaining.

摘要

1982年,作者调查了两组于1972年在斯特拉斯堡大学医院精神科至少住院8天的患者情况。其中一组被诊断为患有“急性妄想发作”(B.D.A.),另一组患有精神分裂症。1982年,前一组有43人,其中26名女性,17名男性;后一组有72人,其中24名女性,48名男性。随访是根据社保档案和医生提供的信息进行整理的。已采取一切可能的预防措施来保护职业秘密和患者的匿名性。对收集到的数据进行统计分析,以确定某些变量之间的相关性,并在此基础上,将传统的法国分类与《精神疾病诊断与统计手册》第三版(D.S.M. III)的分类进行比较。患有急性妄想发作的患者的预后明显好于被视为精神分裂症患者的预后。然而,在1972年被诊断为急性妄想发作的26名患者中,有11人病情发展为精神分裂症,而44名精神分裂症患者中有10人在10年后未出现残障情况。关于传统法国分类法和《精神疾病诊断与统计手册》第三版的预后价值比较,后者在精神分裂症诊断方面似乎更为严格,预后价值可能更明确。这项随访研究进一步支持了急性妄想发作作为一种临床类别存在的观点。在基因、生物学和精神病理学领域进行更深入的研究应该能回答许多仍然存在的问题。

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