Al-Janabi A S, Yousif W H
Ann Rech Vet. 1987;18(1):57-61.
The effects of oxytocin on ovarian function have been studied in immature rats of 25 days of age. The hormone was injected subcutaneously daily for 5 days in two doses: 50 and 250 millimicrons per animal, to intact females, hysterectomized or injected simultaneously with indomethacin (2 mg/kg). Ovarian and uterine weights increased in all treated animals. Plasma estradiol 17 beta levels increased, while plasma progesterone level did not change. The relevance of this study was to precise the trophic role of oxytocin on ovary and uterus. The changes observed did not seem to be associated with prostaglandin E secretion.
已经在25日龄的未成熟大鼠中研究了催产素对卵巢功能的影响。该激素以两种剂量(每只动物50和250毫微克)每天皮下注射5天,注射对象为完整雌性大鼠、子宫切除的雌性大鼠或同时注射消炎痛(2毫克/千克)的雌性大鼠。所有接受治疗的动物的卵巢和子宫重量均增加。血浆17β-雌二醇水平升高,而血浆孕酮水平未发生变化。本研究的意义在于明确催产素对卵巢和子宫的营养作用。观察到的变化似乎与前列腺素E的分泌无关。