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经皮椎体后凸成形术治疗骨质疏松性椎体压缩骨折患者的远段腰骶部疼痛:局部麻醉和类固醇注射。

Local Anesthetic and Steroid Injection to Relieve the Distal Lumbosacral Pain in Osteoporotic Vertebral Compression Fractures of Patients Treated with Kyphoplasty.

机构信息

Department of Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou, China.

出版信息

Pain Physician. 2022 Jul;25(4):E581-E587.

Abstract

BACKGROUND

Percutaneous kyphoplasty (PKP) is widely used in osteoporotic vertebral compression fractures (OVCF). But in some patients, distal lumbosacral pain (DLP) persists even after treatment and affects their quality of life.

OBJECTIVE

To investigate the effectiveness of local anesthetic and steroid injection in improving DLP after PKP.

STUDY DESIGN

A prospective, randomized, and controlled clinical trial.

SETTING

The study was carried out in a university hospital.

METHODS

A total of 150 patients were included in this study and randomly divided into 2 groups of 75 patients each. Patients in the control group (PKP) underwent PKP, and those in the observation group (PKP + LAI) received an injection of lidocaine + triamcinolone acetonide suspensions during the surgery. The visual analog scale (VAS) of the fracture site, Oswestry disability index (ODI), and the rate of patients with lower back pain were compared between the 2 groups at 1 day, 3 days, 1 week, 1 month, and 3 months after the surgery.

RESULTS

One hundred thirty-nine patients completed the entire postoperative follow-up schedule, with 70 patients in the PKP group and 69 cases in the PKP + LAI group. The VAS and ODI in the PKP + LAI group were significantly lower than those in the PKP group 1 day, 3 days, 1 week, and 1 month after the surgery; there was no significant difference  3 months after the operation. The rate of patients with lower back pain in the PKP + LAI group 1 day, 3 days, and 1 week after the operation was significantly lower than that in the control group; there was no significant difference 1 month and 3 months after the operation.

LIMITATIONS

The number of cases was small, and the follow-up time was short.

CONCLUSION

Local anesthetic and steroid injection improved the short-term clinical outcome of PKP for OVCF, which will enhance the confidence of patients in performing out-of-bed activities and functional exercises early after the operation.

摘要

背景

经皮椎体后凸成形术(PKP)广泛应用于骨质疏松性椎体压缩性骨折(OVCF)。但在部分患者中,即使治疗后仍存在腰骶部疼痛(DLP),影响其生活质量。

目的

探讨局部麻醉和类固醇注射对改善 PKP 后 DLP 的效果。

研究设计

前瞻性、随机、对照临床试验。

设置

研究在一所大学医院进行。

方法

共纳入 150 例患者,随机分为 2 组,每组 75 例。对照组(PKP 组)行 PKP,观察组(PKP+LAI 组)在术中行利多卡因+曲安奈德混悬液注射。比较两组患者术后 1 天、3 天、1 周、1 个月和 3 个月时骨折部位视觉模拟评分(VAS)、Oswestry 功能障碍指数(ODI)及下腰痛发生率。

结果

139 例患者完成了整个术后随访,其中 PKP 组 70 例,PKP+LAI 组 69 例。术后 1 天、3 天、1 周和 1 个月,观察组 VAS 和 ODI 均明显低于 PKP 组;术后 3 个月时两组间无显著差异。术后 1 天、3 天和 1 周时观察组下腰痛发生率明显低于对照组;术后 1 个月和 3 个月时两组间无显著差异。

局限性

病例数较少,随访时间较短。

结论

局部麻醉和类固醇注射可改善 OVCF 患者 PKP 的短期临床疗效,增强患者术后早期离床活动和功能锻炼的信心。

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