Ocular Oncology, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, U.S.A.
Pathology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, U.S.A.
Ophthalmic Plast Reconstr Surg. 2022;38(6):e180-e183. doi: 10.1097/IOP.0000000000002236. Epub 2022 Jul 4.
Myxomas are a heterogeneous group of mesenchymal tumors. Soft tissue myxomas are divided into myocardial, intramuscular, juxta-articular, superficial, aggressive, and nerve sheath myxomas. Although benign, myxomas have site-specific biologic behavior and syndromic associations, which can influence prognosis and management. In addition, myxomas need to be distinguished from malignant neoplasms, such as myxofibrosarcomas, low-grade fibromyxoid sarcomas, myxoid liposarcomas, and peripheral nerve sheath tumors. While myxomas can occur throughout the body, these tumors arise more commonly in the thigh, shoulder, buttocks, and upper extremity, and less often in the head and neck. Rarely, myxomas can arise in a periocular location, typically in the conjunctiva and eyelid skin. In this case report, we present a patient with recurrent intramuscular myxoma of the eyelid and discuss the differential diagnosis and syndromic associations of this neoplasm. To our knowledge, there have been no prior reports of intramuscular myxoma of the eyelid and orbit.
黏液瘤是一组异质性的间叶性肿瘤。软组织黏液瘤分为心肌黏液瘤、肌肉内黏液瘤、关节旁黏液瘤、表浅黏液瘤、侵袭性黏液瘤和神经鞘黏液瘤。尽管黏液瘤为良性，但具有特定部位的生物学行为和综合征相关性，这可能影响预后和治疗。此外，黏液瘤需要与恶性肿瘤相鉴别，如黏液纤维肉瘤、低度纤维黏液样肉瘤、黏液样脂肪肉瘤和周围神经鞘肿瘤。虽然黏液瘤可发生于全身各处，但这些肿瘤更常见于大腿、肩部、臀部和上肢，而较少发生于头颈部。罕见情况下，黏液瘤可发生于眶周部位，通常位于结膜和眼睑皮肤。在本病例报告中，我们介绍了 1 例复发性眼睑肌肉内黏液瘤患者，并讨论了该肿瘤的鉴别诊断和综合征相关性。据我们所知，此前尚无眼睑和眼眶内肌肉内黏液瘤的报道。
