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意外接触三氯硅烷泄漏:三例病例报告。

Exposure to an accidental trichlorosilane spill: three case reports.

作者信息

Park Chang Won, Kim Seong Hun, Lee Soo Hyung, Kim Shinwoo, Nho Woo Young

机构信息

Department of Emergency Medicine, Fatima Hospital, Daegu, Korea.

Department of Emergency Medicine, CHA Gumi Medical Center, CHA University School of Medicine, Gumi, Korea.

出版信息

Clin Exp Emerg Med. 2022 Sep;9(3):262-265. doi: 10.15441/ceem.20.149. Epub 2022 Jul 8.

DOI:10.15441/ceem.20.149
PMID:35793790
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9561193/
Abstract

Chlorosilane is a hazardous chemical compound which is used as a raw material in the production of silicone. Despite strict restrictions, accidental spillage of chlorosilane is often reported. However, human exposure was rarely reported in the past decades and the effect on humans is barely known. We report cases of human exposure to an accidental trichlorosilane spill. Three middle aged male industrial workers visited our emergency department after exposure to trichlorosilane. They presented with shortness of breath and burns on multiple sites. Chest radiograph and laboratory studies were performed. None of the reports showed serious results and were discharged after conservative management.

摘要

氯硅烷是一种危险的化合物,用作生产有机硅的原材料。尽管有严格限制,但仍经常有氯硅烷意外泄漏的报告。然而,在过去几十年中,很少有关于人体接触氯硅烷的报告,其对人体的影响也几乎不为人知。我们报告了人体接触三氯硅烷意外泄漏的病例。三名中年男性产业工人在接触三氯硅烷后前往我们的急诊科就诊。他们出现了呼吸急促和多处烧伤。进行了胸部X光检查和实验室检查。所有报告均未显示严重结果,经保守治疗后出院。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8919/9561193/032f3a02e129/ceem-20-149f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8919/9561193/032f3a02e129/ceem-20-149f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8919/9561193/032f3a02e129/ceem-20-149f1.jpg

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本文引用的文献

1
Application of calcium nebulization for mass exposure to an accidental hydrofluoric acid spill.钙雾化在一次意外氢氟酸泄漏大量暴露中的应用。
Burns. 2020 Sep;46(6):1337-1346. doi: 10.1016/j.burns.2020.02.015. Epub 2020 Mar 21.
2
Acute health effects of accidental chlorine gas exposure.意外接触氯气对健康的急性影响。
Ann Occup Environ Med. 2014 Oct 1;26:29. doi: 10.1186/s40557-014-0029-9. eCollection 2014.
3
Chlorosilane acute inhalation toxicity and development of an LC50 prediction model.氯硅烷急性吸入毒性及半数致死浓度(LC50)预测模型的建立
Inhal Toxicol. 2006 Jul;18(8):515-22. doi: 10.1080/08958370600686093.
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Health effects of silicon tetrachloride. Report of an urban accident.四氯化硅对健康的影响。城市事故报告。
J Occup Med. 1984 Jan;26(1):33-6. doi: 10.1097/00043764-198401000-00008.