Tazhikova Aigul, Makishev Abay, Bekisheva Aizhan, Dmitriyeva Mariya, Toleubayev Medet, Sabitova Alina
Departments of Oncology, Astana Medical University, Nur-Sultan, Kazakhstan.
Departments of Plastic Surgery, Astana Medical University, Nur-Sultan, Kazakhstan.
Ann Rehabil Med. 2022 Jun;46(3):142-153. doi: 10.5535/arm.22025. Epub 2022 Jun 30.
To systematically review the available literature on the efficacy of tibial nerve stimulation on faecal incontinence and quality of life in adult patients with low anterior resection syndrome following surgery for colorectal cancer.
A primary search of electronic databases was conducted adopting a combination of search terms related to the following areas of interest: "efficacy", "tibial nerve stimulation" and "low anterior resection syndrome". A secondary search of the grey literature was performed in addition to checking the reference list of included studies and review papers. The review was reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. A descriptive analysis was used to integrate the review findings.
Five distinct studies involving 116 patients met the inclusion criteria for the review. The included studies suggest that tibial nerve stimulation may have a positive effect on faecal incontinence and quality of life in some patients with low anterior resection syndrome and might be considered as an additional treatment option.
There were a limited number of studies and a great degree of heterogeneity of evidence due to differences in participants' baseline characteristics, dropout rates, and follow-up periods. Further research adopting validated, consistent, and complex outcome assessment methods is recommended to determine the efficacy of tibial nerve stimulation for treatment of patients with low anterior resection syndrome.
系统回顾关于胫神经刺激对成年直肠癌手术后低位前切除综合征患者大便失禁及生活质量疗效的现有文献。
采用与以下感兴趣领域相关的搜索词组合对电子数据库进行初步检索：“疗效”、“胫神经刺激”和“低位前切除综合征”。除了检查纳入研究和综述论文的参考文献列表外，还对灰色文献进行了二次检索。本综述按照系统评价和Meta分析的首选报告项目指南进行报告。采用描述性分析来整合综述结果。
五项涉及116例患者的不同研究符合本综述的纳入标准。纳入研究表明，胫神经刺激可能对一些低位前切除综合征患者的大便失禁和生活质量有积极影响，可被视为一种额外的治疗选择。
由于参与者的基线特征、失访率和随访期存在差异，研究数量有限且证据异质性较大。建议采用经过验证、一致且复杂的结局评估方法进行进一步研究，以确定胫神经刺激治疗低位前切除综合征患者的疗效。
