Department of Hematology and Oncology, Kobe Children's Hospital, Japan.
Department of Neurosurgery, Kobe Children's Hospital, Japan.
Intern Med. 2023 Feb 1;62(3):453-457. doi: 10.2169/internalmedicine.9580-22. Epub 2022 Jul 5.
We herein report a rare case of spinal cord compression due to epidural involvement of acute myeloid leukemia (AML). A 14-year-old boy presented with a 7-day history of back pain, paraplegia and hypoesthesia. Contrast-enhanced computed tomography revealed an epidural mass. Emergency laminectomy and resection of the mass were performed. Histopathologically, the resected mass was comparable to an extramedullary mass of AML. Chemotherapy was initiated, and complete remission was achieved. Neurological sequelae remained after the treatment. Based on the present and previous reports, spinal cord compression from epidural AML involvement may progress rapidly.
我们在此报告一例因急性髓系白血病（AML）硬膜外累及导致的脊髓压迫症。一名 14 岁男孩因背痛、截瘫和感觉减退 7 天就诊。增强 CT 显示硬膜外肿块。行急诊椎板切除术和肿块切除术。病理检查发现切除的肿块与 AML 的髓外肿块相似。开始化疗，达到完全缓解。治疗后仍存在神经后遗症。根据目前和以往的报告，硬膜外 AML 累及导致的脊髓压迫可能会迅速进展。
