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Thrombocytopenia, anasarca, and severe inflammation.血小板减少、全身性水肿和严重炎症。
Am J Hematol. 2022 Oct;97(10):1374-1380. doi: 10.1002/ajh.26651. Epub 2022 Jul 19.
2
Japanese variant of multicentric castleman's disease associated with serositis and thrombocytopenia--a report of two cases: is TAFRO syndrome (Castleman- Kojima disease) a distinct clinicopathological entity?与浆膜炎和血小板减少症相关的多中心性Castleman病日本变异型——两例报告：TAFRO综合征（Castleman - 小岛病）是一种独特的临床病理实体吗？
J Clin Exp Hematop. 2013;53(1):79-85. doi: 10.3960/jslrt.53.79.
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TAFRO syndrome: 2 cases and review of the literature.TAFRO综合征：2例病例及文献综述
Mod Rheumatol. 2017 Nov;27(6):1093-1097. doi: 10.3109/14397595.2015.1059982. Epub 2015 Jul 20.
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Hepatic Campylobacter jejuni infection in patients with Castleman-Kojima disease (idiopathic multicentric Castleman disease with thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly (TAFRO) syndrome).患者出现肝弯曲杆菌空肠亚种感染（特发性多中心 Castleman 病伴血小板减少、全身性水肿、发热、网状纤维纤维化和器官肿大（TAFRO）综合征）。
Pathol Int. 2019 Oct;69(10):572-579. doi: 10.1111/pin.12856.
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A severe case of thrombocytopenia, anasarca, fever, renal insufficiency or reticulin fibrosis, and organomegaly syndrome with myocardial and skeletal muscle calcification despite hypocalcemia: a case report.一例严重血小板减少、全身性水肿、发热、肾功能不全或网状纤维组织增生以及尽管存在低钙血症但伴有心肌和骨骼肌钙化的器官肿大综合征：病例报告
J Med Case Rep. 2021 Jan 6;15(1):3. doi: 10.1186/s13256-020-02588-2.
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TAFRO syndrome: A severe manifestation of Sjogren's syndrome? A systematic review.TAFRO 综合征：干燥综合征的严重表现？系统综述。
Autoimmun Rev. 2022 Aug;21(8):103137. doi: 10.1016/j.autrev.2022.103137. Epub 2022 Jul 6.
7
Multifocal Castleman disease in pediatrics: case report.小儿多灶性Castleman病：病例报告
J Pediatr Hematol Oncol. 2005 Dec;27(12):666-9. doi: 10.1097/01.mph.0000193468.06938.93.
8
Unexplained cause of thrombocytopenia, fever, anasarca and hypothyroidism: TAFRO syndrome with thrombotic microangiopathy renal histology.血小板减少症、发热、全身水肿和甲状腺功能减退的不明原因：伴有血栓性微血管病肾组织学的 TAFRO 综合征。
BMJ Case Rep. 2020 Jun 30;13(6):e234155. doi: 10.1136/bcr-2019-234155.
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TAFRO Syndrome Presenting with Retroperitoneal Panniculitis-like Computed Tomography Findings at Disease Onset.TAFRO综合征在疾病发作时表现为腹膜后脂膜炎样计算机断层扫描结果。
Intern Med. 2020 Apr 1;59(7):997-1000. doi: 10.2169/internalmedicine.3740-19. Epub 2019 Dec 13.
10
TAFRO Syndrome.TAFRO综合征
Hematol Oncol Clin North Am. 2018 Feb;32(1):107-118. doi: 10.1016/j.hoc.2017.09.009.

引用本文的文献

1
Idiopathic multicentric Castleman disease - TAFRO results in high levels of mTOR activator SVEP1, tissue factor, and endotheliopathy.特发性多中心Castleman病 - TAFRO综合征导致高水平的mTOR激活剂SVEP1、组织因子和内皮病变。
Blood Vessel Thromb Hemost. 2024 Jun;1(2). doi: 10.1016/j.bvth.2024.100006. Epub 2024 Apr 3.
2
Case report: Importance of early and continuous tocilizumab therapy in nephrotic syndrome associated with idiopathic multicentric Castleman disease: A case series.病例报告：托珠单抗早期持续治疗在特发性多中心Castleman病相关肾病综合征中的重要性：病例系列
Front Med (Lausanne). 2023 Jan 9;9:1037032. doi: 10.3389/fmed.2022.1037032. eCollection 2022.

本文引用的文献

1
Idiopathic multicentric Castleman disease with arteriolar endotheliopathy and secondary haemophagocytosis.伴有小动脉内皮病变及继发性噬血细胞作用的特发性多中心Castleman病
Lancet Haematol. 2022 Jul;9(7):e546. doi: 10.1016/S2352-3026(22)00037-0.
2
Bone marrow findings of idiopathic Multicentric Castleman disease: A histopathologic analysis and systematic literature review.特发性多中心 Castleman 病的骨髓表现：组织病理学分析和系统文献复习。
Hematol Oncol. 2022 Apr;40(2):191-201. doi: 10.1002/hon.2969. Epub 2022 Feb 18.
3
Malignancy-associated haemophagocytic lymphohistiocytosis.恶性肿瘤相关性噬血细胞性淋巴组织细胞增生症。
Lancet Haematol. 2022 Mar;9(3):e217-e227. doi: 10.1016/S2352-3026(21)00366-5. Epub 2022 Jan 31.
4
Discovery and validation of a novel subgroup and therapeutic target in idiopathic multicentric Castleman disease.特发性多中心Castleman病中一个新亚组及治疗靶点的发现与验证
Blood Adv. 2021 Sep 14;5(17):3445-3456. doi: 10.1182/bloodadvances.2020004016.
5
Validated international definition of the thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly clinical subtype (TAFRO) of idiopathic multicentric Castleman disease.特发性多中心 Castleman 病伴血小板减少、浮肿、发热、网状纤维纤维化、肾功能不全和器官肿大（TAFRO）临床亚型的验证性国际定义。
Am J Hematol. 2021 Oct 1;96(10):1241-1252. doi: 10.1002/ajh.26292. Epub 2021 Jul 28.
6
Adrenalitis and anasarca in idiopathic multicentric Castleman's disease.特发性多中心Castleman病中的肾上腺炎和全身性水肿
Lancet. 2021 May 8;397(10286):1749. doi: 10.1016/S0140-6736(21)00674-7.
7
Patient's age and D-dimer levels predict the prognosis in patients with TAFRO syndrome.患者的年龄和 D-二聚体水平可预测 TAFRO 综合征患者的预后。
Int J Hematol. 2021 Aug;114(2):179-188. doi: 10.1007/s12185-021-03159-x. Epub 2021 Apr 30.
8
Soluble interleukin-6 receptor in the COVID-19 cytokine storm syndrome.可溶性白细胞介素-6 受体在 COVID-19 细胞因子风暴综合征中的作用。
Cell Rep Med. 2021 May 18;2(5):100269. doi: 10.1016/j.xcrm.2021.100269. Epub 2021 Apr 19.
9
Polyclonal hypergammaglobulinaemia: assessment, clinical interpretation, and management.多克隆高丙种球蛋白血症：评估、临床解读和管理。
Lancet Haematol. 2021 May;8(5):e365-e375. doi: 10.1016/S2352-3026(21)00056-9.
10
Cytokine Storm.细胞因子风暴
N Engl J Med. 2020 Dec 3;383(23):2255-2273. doi: 10.1056/NEJMra2026131.

Thrombocytopenia, anasarca, and severe inflammation.

作者信息

Montazeripouragha Amanallah, Campbell Christine M, Russell James, Medvedev Nadia, Owen Daniel R, Harris Alison, Donnellan Fergal, McCormick Iain, Fajgenbaum David C, Chen Luke Y C

机构信息

Internal Medicine Residency Program, Department of Medicine, University of British Columbia, Vancouver, Canada.

Department of Radiology, University of British Columbia, Vancouver, Canada.

出版信息

Am J Hematol. 2022 Oct;97(10):1374-1380. doi: 10.1002/ajh.26651. Epub 2022 Jul 19.

DOI:10.1002/ajh.26651
PMID:35794839
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9555220/
Abstract
摘要