Epidemiology of Physical Activity and Fitness Across the Lifespan (EPAFit) Research Group, Faculty of Education, Department of Physical Education and Sports, University of Seville, Seville, Spain.
Epidemiology of Physical Activity and Fitness Across the Lifespan (EPAFit) Research Group. Department of Physical Activity and Sport, Cardeal Spinola CEU, Seville, Spain.
Diabetes Care. 2022 Sep 1;45(9):2156-2158. doi: 10.2337/dc22-0524.
We aimed to examine the dose-response associations between the number of steps per day and all-cause mortality among adults with prediabetes and diabetes.
This prospective study used data from 1,194 U.S. adults with prediabetes and 493 with diabetes for whom accelerometer-derived steps per day could be retrieved. Mortality was ascertained through the National Death Index (February 25, 2019). Splines were used to assess the dose-response associations between steps per day and all-cause mortality.
Over ∼9 years of follow-up, 200 adults with prediabetes and 138 with diabetes died. Nonlinear associations akin to an L shape were observed. We estimated an optimal dose of ∼10,000 steps per day to reduce the risk of all-cause mortality for both individuals with prediabetes and those with diabetes.
Accumulating more steps per day up to ∼10,000 steps per day may lower the risk of all-cause mortality of adults with prediabetes and diabetes.
本研究旨在探讨成年人中糖尿病前期和糖尿病患者每天步数与全因死亡率之间的剂量-反应关系。
本前瞻性研究使用了来自美国 1194 名糖尿病前期和 493 名糖尿病患者的数据,这些患者的加速度计可以获取每天的步数。通过国家死亡索引(2019 年 2 月 25 日)确定死亡率。样条用于评估每天步数与全因死亡率之间的剂量-反应关系。
在大约 9 年的随访期间,200 名糖尿病前期患者和 138 名糖尿病患者死亡。观察到类似于 L 形的非线性关联。我们估计每天约 10000 步是一个最佳的剂量,可以降低糖尿病前期和糖尿病患者全因死亡率的风险。
每天增加更多的步数,达到每天约 10000 步,可能会降低糖尿病前期和糖尿病成年人的全因死亡率风险。