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绝经、皮肤和常见皮肤病。第 1 部分:毛发疾病。

Menopause, skin and common dermatoses. Part 1: hair disorders.

机构信息

Department of Dermatology, University Hospitals Sussex NHS Foundation Trust, Brighton, UK.

出版信息

Clin Exp Dermatol. 2022 Dec;47(12):2110-2116. doi: 10.1111/ced.15327. Epub 2022 Oct 28.

Abstract

Menopause, which usually occurs between the age of 45 and 55 years, is associated with falling oestrogen levels due to ovarian follicle depletion. The impact on the cardiovascular system and bone density are well documented; however, further research required to establish the impact on the skin and hair. In this first part of a four-part review, we examine the effect of menopause on the hair. We performed a literature review on dermatology and hair in menopause. Androgens and oestrogens are involved with regulation of the hair cycle, with a reduction in anagen hairs seen in postmenopausal women. Female pattern hair loss and frontal fibrosing alopecia have both been associated with the perimenopausal and postmenopausal states. It is clear that menopause and the change in hormone levels have an impact on the hair cycle and common hair conditions. However, further research is required, particularly to understand the therapeutic targets and role of hormonal therapy.

摘要

绝经期通常发生在 45 岁至 55 岁之间,由于卵巢卵泡耗竭,雌激素水平下降。心血管系统和骨密度的影响已有充分的记录;然而,还需要进一步的研究来确定其对皮肤和头发的影响。在这四部分综述的第一部分中,我们研究了绝经期对头发的影响。我们对皮肤科和绝经期头发进行了文献回顾。雄激素和雌激素参与了毛发生长周期的调节,绝经后妇女的生长期毛发减少。女性型脱发和额部纤维性脱发都与围绝经期和绝经后状态有关。很明显,绝经期和激素水平的变化对毛发生长周期和常见的头发状况有影响。然而,还需要进一步的研究,特别是为了了解治疗靶点和激素治疗的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf3/10092469/90ab2e2d1a1c/CED-47-2110-g002.jpg

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