Department of Dermatology, University Hospitals Sussex NHS Foundation Trust, Brighton, UK.
Clin Exp Dermatol. 2022 Dec;47(12):2117-2122. doi: 10.1111/ced.15308. Epub 2022 Oct 26.
In this second part of a four-part review, we examine the effect of menopause on the skin. Menopause and the associated hypo-oestrogenic state have implications for the structure and function of the skin. We performed a literature review to investigate the impact of the menopause on common dermatoses. There is evidence that oestrogen is implicated in transepidermal water loss and reduction in dermal collagen. There are associations with menopause and multiple common dermatoses, including xerosis and pruritus, hidradenitis suppurativa and psoriasis. Menopause has a clear impact on the skin and common dermatological conditions. Further research to understand the mechanisms and explore therapeutic options is needed.
在这篇四部分综述的第二部分中,我们研究了绝经对皮肤的影响。绝经和随之而来的低雌激素状态会影响皮肤的结构和功能。我们进行了文献回顾,以研究绝经对常见皮肤病的影响。有证据表明,雌激素与经皮水分流失和真皮胶原蛋白减少有关。绝经与多种常见皮肤病有关,包括干燥和瘙痒、化脓性汗腺炎和银屑病。绝经对皮肤和常见皮肤病有明显影响。需要进一步研究以了解其机制并探索治疗选择。