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人类体感诱发电位N20成分的起源。

The origin of the N20 component of the somatosensory evoked potential in man.

作者信息

Shaw N A

出版信息

Aust J Exp Biol Med Sci. 1986 Oct;64 ( Pt 5):471-5. doi: 10.1038/icb.1986.50.

DOI:10.1038/icb.1986.50
PMID:3579741
Abstract

Somatosensory evoked potentials (SEPs) were recorded from a 63 year old male who had sustained severe right sided cortical damage including infarction of the primary sensory hand area. When SEPs were recorded following right median nerve stimulation, both cervical and cortical waveforms were of normal configuration. When SEPs were recorded following left median nerve stimulation, the cervical potential was intact but the cortical waveform was absent and replaced with a positive-negative complex which was probably a far field reflection of thalamic activity. These findings suggest that the first negative component of the cortical SEP (N20) is not generated in the diencephalon but represents the initial response of the somatosensory cortex.

摘要

对一名63岁男性进行体感诱发电位(SEP)记录,该男性右侧皮质遭受严重损伤,包括初级感觉手部区域梗死。在右侧正中神经刺激后记录SEP时,颈部和皮质波形的形态均正常。在左侧正中神经刺激后记录SEP时,颈部电位完整,但皮质波形缺失,取而代之的是一个正负复合波,这可能是丘脑活动的远场反射。这些发现表明,皮质SEP的第一个负向成分(N20)并非在间脑产生,而是代表体感皮层的初始反应。

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