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具有卵巢扭转特征的卵巢小细胞癌:一例细胞病理学难题病例。

Ovarian small cell carcinoma by ovarian torsion feature: A cytopathology challenging case.

作者信息

Keikha Fatemeh, Hadizadeh Alireza, Akhavan Setareh, Nili Fatemeh, Eshghinejad Arefeh, Ghaemi Marjan

机构信息

Vali-E-Asr Reproductive Health Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Int J Surg Case Rep. 2022 Jul;96:107337. doi: 10.1016/j.ijscr.2022.107337. Epub 2022 Jun 22.

Abstract

INTRODUCTION AND IMPORTANCE

Ovarian small cell carcinomas are a rare type of ovarian cancer that is highly aggressive and consists of two distinct types the hypercalcemic type (SCCOHT) and pulmonary type (SCCOPT).

CASE PRESENTATION

A 23 years old girl was admitted to the emergency room with the presentation of acute abdomen. The ultrasound and Magnetic resonance imaging revealed a right adnexal huge mass with adnexal torsion. In laparotomy, she underwent unilateral salpingo-oophorectomy due to ovarian torsion and possible malignancy. The histopathological evaluation was challenging and was finalized by a team of pathologists as hypercalcemic small cell carcinoma. She refused reoperation and unfortunately relapsed during chemotherapy and died 6 months after the initial diagnosis.

CLINICAL DISCUSSION

Conclusion: We do not yet have comprehensive information on small cell ovarian cancer. Cytopathology diagnosis is still challenging and the treatments are not usually effective. Further clinical trials and studies are recommended to find appropriate treatments for these patients.

摘要

引言与重要性

卵巢小细胞癌是一种罕见的卵巢癌类型,侵袭性很强,由两种不同类型组成,即高钙血症型(SCCOHT)和肺型(SCCOPT)。

病例介绍

一名23岁女孩因急腹症被收入急诊室。超声和磁共振成像显示右侧附件有一个巨大肿块伴附件扭转。在剖腹手术中,由于卵巢扭转和可能的恶性肿瘤,她接受了单侧输卵管卵巢切除术。组织病理学评估具有挑战性,一组病理学家最终确定为高钙血症小细胞癌。她拒绝再次手术,不幸的是在化疗期间复发,并在初次诊断后6个月死亡。

临床讨论

结论:我们尚未掌握关于卵巢小细胞癌的全面信息。细胞病理学诊断仍然具有挑战性,治疗通常也无效。建议进一步开展临床试验和研究,为这些患者找到合适的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df5c/9284065/ecc348876eb3/gr1.jpg

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