Khosla Divya, Gupta Nalini, Koshy Abin, Dalal Ashwani, Pandey A K, Dimri Kislay
1Department of Radiotherapy and Oncology, Government Medical College and Hospital, Chandigarh, India.
2Department of Cytology and Gynaecological Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012 India.
J Obstet Gynaecol India. 2019 Apr;69(Suppl 1):60-62. doi: 10.1007/s13224-018-1091-y. Epub 2018 Feb 2.
Small cell carcinoma of ovary, hypercalcemic type is a rare malignancy with a dismal prognosis. The diagnosis is often confused with many other tumors.
We describe a rare case of ovarian small cell carcinoma of hypercalcemic type in an adolescent. She presented with abdominal pain, awareness of mass and vomiting. She underwent exploratory laparotomy and right ovarian excision. The detailed histopathological examination including immunohistochemistry was suggestive of ovarian small cell carcinoma of hypercalcemic type. She had progressive disease on chemotherapy and ultimately died within 2 years of diagnosis. Due to rarity of this neoplasm and its aggressive nature, the optimal treatment regimen has not been established.
We report this case because of its rare occurrence leading to clinical and diagnostic challenges and need to explore effective treatment options to improve survival in these patients.
高钙血症型卵巢小细胞癌是一种罕见的恶性肿瘤，预后不佳。其诊断常与许多其他肿瘤相混淆。
我们描述了一例青少年高钙血症型卵巢小细胞癌的罕见病例。她表现为腹痛、腹部肿块感和呕吐。她接受了剖腹探查和右侧卵巢切除术。包括免疫组化在内的详细组织病理学检查提示为高钙血症型卵巢小细胞癌。她在化疗期间病情进展，最终在确诊后2年内死亡。由于这种肿瘤罕见且具有侵袭性，尚未确立最佳治疗方案。
我们报告此病例是因为其罕见性导致临床和诊断方面的挑战，并且需要探索有效的治疗方案以提高这些患者的生存率。
