Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada; The Children's Hospital Research Institute of Manitoba, Winnipeg, MB R3E 3P4, Canada; Program in Biomedical Engineering, University of Manitoba, Winnipeg, MB Canada.
Neuron. 2022 Jul 6;110(13):2041-2044. doi: 10.1016/j.neuron.2022.06.005.
Neuronal wiring is facilitated by diverse synaptic adhesion proteins and their repertoire of alternatively spliced isoforms. In this issue of Neuron, Hauser et al. (2022) uncovered the role of a GPI-anchored neurexin 3 splice variant in inhibitory synapse development and dendritic inhibition.
神经元连接是由多种突触黏附蛋白及其选择性剪接异构体的组合来促进的。在本期《神经元》杂志中，Hauser 等人（2022）揭示了 GPI 锚定神经连接蛋白 3 剪接变体在抑制性突触发育和树突抑制中的作用。
