Kakeue Ken, Mihara Miharu, Tamura Ryoi, Hayashi Atsushi
Department of Ophthalmology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama.
Department of Integrative Neuroscience, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama.
Strabismus. 2022 Sep;30(3):121-131. doi: 10.1080/09273972.2022.2097708. Epub 2022 Jul 7.
In patients with intermittent exotropia (IXT), to investigate the correlation between fusional convergence amplitude and saccade during refusion, as well as the differences in saccade caused by suppression. We measured the fusional convergence amplitude using a synoptophore. Suppression was assessed in 15 patients with IXT (mean age 18.1 ± 11.0 yrs, range 8-54 yrs) having diplopia during exotropia. We performed the cover-uncover test and recorded the saccade during the shift from exotropia to binocular fixation using an eye-tracking system. We analyzed the correlation between the fusional convergence amplitude on the one hand and the saccade peak velocity (PV), the saccade amplitude, and the saccade amplitude of the fusion on the other. We also investigated the difference of those saccade variables between patients with and without suppression. In 15 patients with IXT, the median fusional convergence amplitude was 14 (range 0-60) °, and suppression was confirmed in 11 patients. When the cover was removed from the dominant eye, the fusional convergence amplitude showed a positive correlation with the saccade PV and the amplitude in non-dominant eye (r = 0.570, p = 0.042 and r = 0.669, p = 0.012, respectively). The mean saccade PV, the mean saccade amplitude and the mean saccade amplitude of the fusion were not significantly different with the presence or the absence of the suppression. The fusional convergence amplitude was correlated with saccade in patients with IXT. The saccade during refusion can thus be used to quantitatively evaluate sensory and/or motor fusion.
在间歇性外斜视（IXT）患者中，研究融合性集合幅度与再融合期间扫视之间的相关性，以及由抑制引起的扫视差异。我们使用同视机测量融合性集合幅度。对15例外斜视期间出现复视的IXT患者（平均年龄18.1±11.0岁，范围8 - 54岁）进行抑制评估。我们进行遮盖 - 去遮盖试验，并使用眼动追踪系统记录从外斜视转变为双眼注视期间的扫视。我们分析了一方面融合性集合幅度与另一方面扫视峰值速度（PV）、扫视幅度和融合扫视幅度之间的相关性。我们还研究了有抑制和无抑制患者之间这些扫视变量的差异。在15例IXT患者中，融合性集合幅度的中位数为14（范围0 - 60）°，11例患者被证实存在抑制。当遮盖从优势眼移除时，融合性集合幅度与非优势眼的扫视PV和幅度呈正相关（分别为r = 0.570，p = 0.042和r = 0.669，p = 0.012）。有抑制和无抑制时，平均扫视PV、平均扫视幅度和平均融合扫视幅度无显著差异。IXT患者的融合性集合幅度与扫视相关。因此，再融合期间的扫视可用于定量评估感觉和/或运动融合。
