Department of Cardiology, BM Birla Heart Research Centre, Kolkata, West Bengal, India.
Department of Cardiology, Max Hospital, Purnia, Bihar, India.
Ann Card Anaesth. 2022 Jul-Sep;25(3):264-269. doi: 10.4103/aca.aca_35_21.
The objectives of this study were to find out of normal reference value for age-dependent longitudinal strain values in children and find its correlation with conventional echocardiographic parameters.
In total, 100 healthy normal children aged between 2 and 15 years were enrolled and divided into three age groups, namely, 2-5 years, 5-10 years, and 10-15 years. Using the GE Vivid 7 ultrasound platform with 4 or 7 MHz probes, both LV and RV global longitudinal strains and conventional echocardiographic parameters were acquired.
In normal healthy children, left ventricular GLS values were -20.10 to -19.68 (mean: -19.89), -21.93 to -21.02 (mean: -21.48), and -20.87 to -20.41 (mean: -20.64)) in children aged 2-5 years, 5-10 years, and 10-15 years and right ventricular GLS values were -16.80 to -16.44 (mean: -16.62), -27.85 to -27.27 (mean: -27.56), -28.44 to -27.93 (mean: -28.19) in the above three groups, respectively. No significant increase was noted in the left ventricular strain value from basal to the apical segment from age group 2 years to 15 years and no gender differences were seen. None of the conventional echocardiographic parameters commonly used to assess the left or right ventricular systolic function had a significant correlation with LVGLS and RVGLS.
The mean LVGLS values were -19.89, -21.48, and -20.64 and RVGLS were -16.62, -27.56, and -28.19 in healthy normal children aged 2-5 years, 5-10 years, and 10-15 years, respectively, and conventional echocardiographic parameters did not have any significant correlation with these values.
本研究旨在确定儿童年龄相关纵向应变值的正常参考值，并探讨其与常规超声心动图参数的相关性。
共纳入 100 例 2-15 岁健康正常儿童，分为 2-5 岁、5-10 岁和 10-15 岁 3 个年龄组。使用 GE Vivid 7 超声平台及 4 或 7 MHz 探头，获取左、右心室整体纵向应变及常规超声心动图参数。
正常健康儿童左心室 GLS 值分别为 2-5 岁组-20.10 至-19.68（均值：-19.89）、5-10 岁组-21.93 至-21.02（均值：-21.48）和 10-15 岁组-20.87 至-20.41（均值：-20.64），右心室 GLS 值分别为 2-5 岁组-16.80 至-16.44（均值：-16.62）、5-10 岁组-27.85 至-27.27（均值：-27.56）和 10-15 岁组-28.44 至-27.93（均值：-28.19），从 2 岁组到 15 岁组，左心室应变值从基底段到心尖段未见明显增加，且无性别差异。左、右心室收缩功能常用的常规超声心动图参数与 LVGLS 和 RVGLS 均无显著相关性。
健康正常儿童左心室 GLS 值分别为-19.89、-21.48 和-20.64，右心室 GLS 值分别为-16.62、-27.56 和-28.19，常规超声心动图参数与这些值均无显著相关性。
