Department of Ultrasound, The Fourth Hospital of Shijiazhuang, Shijiazhuang, 050000 Hebei, China.
Comput Math Methods Med. 2022 Jun 28;2022:6110228. doi: 10.1155/2022/6110228. eCollection 2022.
Colour Doppler ultrasound was applied for monitoring the hemodynamic parameters of fetal uterine artery (UtA), umbilical artery (UA), and middle cerebral artery (MCA) during pregnancy. In hypertension disease complicating pregnancy, these hemodynamic measures and their therapeutic applicability value were reviewed (HDCP). 120 singleton pregnant women were chosen, with 40 cases of mild preeclampsia (mild group), 40 cases of severe preeclampsia (severe group), and 40 normal control pregnant women (control group). The hemodynamic parameters of UtA, MCA, and UA were monitored in the three groups, including pulsatility index (PI), resistance index (RI), and the systolic/diastolic velocity (S/D). The parameters PI, RI, S/D, and venous catheter shunt rate (Qdv/Quv) of UtA and UA in the severe group were higher than those in the normal group and the mild group, showing the differences statistically significant ( < 0.05). The PI, RI, and S/D of MCA in the severe group were lower than those in the normal group and the mild group ( < 0.05). The changing trends of PI, RI, and S/D in the severe group were all first increased and then decreased in the early, middle, and later pregnancy ( < 0.05). The area under the curve (AUC) was 0.98 in the receiver operating characteristic (ROC) curve created using a combination of hemodynamic measures and pregnancy outcomes, and the sensitivity and specificity for predicting bad outcomes were 94.7 percent and 96.4 percent, respectively. Colour Doppler ultrasound may accurately detect changes in the PI, RI, and S/D of UtA, MCA, and UA in pregnant women and serve as a reference for determining the intrauterine state of the fetuses and predicting bad pregnancy outcomes. In particular, the parameters in later pregnancy were higher worthy of diagnostic value for adverse pregnancy outcomes. The combination of various parameters could make an improvement of the diagnostic accuracy and provide a basis for guiding treatment as well as determining the optimal timing of delivery.
彩色多谱勒超声用于监测妊娠期间胎儿子宫动脉（UtA）、脐动脉（UA）和大脑中动脉（MCA）的血流动力学参数。在妊娠合并高血压疾病中，回顾了这些血流动力学测量及其治疗适用性价值（HDCP）。选择了 120 名单胎孕妇，其中 40 例轻度子痫前期（轻度组），40 例重度子痫前期（重度组），40 例正常对照组孕妇。监测三组 UtA、MCA 和 UA 的血流动力学参数，包括搏动指数（PI）、阻力指数（RI）和收缩/舒张速度（S/D）。重度组 UtA 和 UA 的参数 PI、RI、S/D 和静脉导管分流率（Qdv/Quv）均高于正常组和轻度组，差异有统计学意义（<0.05）。重度组 MCA 的 PI、RI 和 S/D 均低于正常组和轻度组（<0.05）。重度组 PI、RI 和 S/D 的变化趋势在早、中、晚期妊娠均为先升高后降低（<0.05）。采用血流动力学指标联合妊娠结局绘制受试者工作特征（ROC）曲线，曲线下面积（AUC）为 0.98，预测不良结局的敏感性和特异性分别为 94.7%和 96.4%。彩色多谱勒超声可准确检测孕妇 UtA、MCA 和 UA 的 PI、RI 和 S/D 变化，为判断胎儿宫内状态和预测不良妊娠结局提供参考。特别是妊娠晚期的参数对不良妊娠结局有更高的诊断价值。各种参数的联合应用可以提高诊断准确性，并为指导治疗以及确定最佳分娩时机提供依据。
