Dominici Carmelo, Chello Massimo, Saeed Sahrai
Carmelo Dominici, MD, Department of Cardiac Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
Massimo Chello, MD, Department of Cardiac Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
Pak J Med Sci. 2022 May-Jun;38(5):1395-1400. doi: 10.12669/pjms.38.5.5674.
Coronary artery bypass grafting (CABG) is a widely used surgical procedure which improves clinical outcomes in appropriately selected patients. Conventionally, the greater saphenous vein is often used in CABG. However, due to their higher long-term patency rates, arterial conduits are routinely used, with the left internal thoracic artery (LITA) on left anterior descending (LAD) being the gold standard in CABG. Our aim in the present work was to investigate the outcomes of a total arterial grafting (TAG) on the whole heart, with no use of venous grafts, compared to mixed conduits in real-world data. A literature search was conducted in the bibliographic databases PubMed and Web of Science. Only studies comparing TAG with conventional CABG (at least one venous graft plus one or more arterial grafts), with at least one hundred patients in each group were included in this review. After study selection, a total of 15 relevant studies were evaluated and discussed in the present review. Results indicated that TAG is a highly efficient technique, and multiple arterial grafts can be used to reliably revascularize all coronary artery territories. TAG was more beneficial in terms of both short and long-term outcomes and its use should be encouraged. Large randomized clinical trials are needed to confirm the superiority of total arterial grafting with regard to long-term outcomes.
冠状动脉旁路移植术(CABG)是一种广泛应用的外科手术,能改善适当选择的患者的临床结局。传统上,大隐静脉常用于冠状动脉旁路移植术。然而,由于动脉移植物具有更高的长期通畅率,因此常规使用动脉移植物,其中左前降支(LAD)上的左乳内动脉(LITA)是冠状动脉旁路移植术的金标准。我们目前这项工作的目的是,在真实世界数据中,研究全动脉移植(TAG)即不使用静脉移植物对整个心脏进行移植的结果,并与混合移植物进行比较。我们在文献数据库PubMed和Web of Science中进行了文献检索。本综述仅纳入了比较全动脉移植与传统冠状动脉旁路移植术(至少一根静脉移植物加一根或多根动脉移植物)且每组至少有100例患者的研究。经过研究筛选,本综述共评估和讨论了15项相关研究。结果表明,全动脉移植是一种高效的技术,多条动脉移植物可用于可靠地使所有冠状动脉区域血管再通。全动脉移植在短期和长期结局方面都更有益,应鼓励使用。需要大型随机临床试验来证实全动脉移植在长期结局方面的优越性。