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妊娠糖尿病患者巨大儿的预测因素及妊娠结局:沙特阿拉伯哈伊勒的一项观察性研究

Macrosomia predictors and pregnancy outcomes in Gestational Diabetes patients: An observational study from Ha'il, Saudi Arabia.

作者信息

Parveen Nuzhat, Iqbal Naveed, Batool Asma, Mahmoud Tariq, Ali Syeda

机构信息

Nuzhat Parveen, Assistant Professor, Department of Obstetrics and Gynecology, College of Medicine, University of Ha'il, Ha'il-81451, Kingdom of Saudi Arabia KSA.

Naveed Iqbal, Associate Professor, Department of Obstetrics and Gynecology, College of Medicine, University of Ha'il, Ha'il-81451, Kingdom of Saudi Arabia KSA.

出版信息

Pak J Med Sci. 2022 May-Jun;38(5):1126-1131. doi: 10.12669/pjms.38.5.5809.

Abstract

OBJECTIVES

To determine the prevalence, risk factors for macrosomia and pregnancy outcome in women with gestational diabetes (GDM).

METHODS

In this prospective observational study, we included the data of 161 pregnant females diagnosed with GDM. The study was conducted from December 1st, 2020 to June 30, 2021, at the Maternity and Children Hospital (MCH) of Hail, Saudi Arabia. The data regarding risk factors of macrosomia was obtained from each patient. The patients were followed till the delivery of the baby. The data regarding the prevalence of fetal macrosomia and its associated outcomes was noted.

RESULTS

The prevalence of fetal macrosomia was 19.8%. Maternal obesity (OR 4.87), poorly controlled diabetes (OR 3.3), previous history of good-sized baby (OR 2.30), previous history of congenital abnormalities (OR 7.2) were the significant risk factors of fetal macrosomia. The prevalence of maternal and fetal complications was high among pregnancies complicated by fetal macrosomia. The prevalence of fetal macrosomia and other fetal complications was high in poorly controlled GDM patients in comparison to optimal control GDM patients.

CONCLUSION

Fetal macrosomia is a common complication among GDM patients. Maternal obesity and poorly controlled diabetes are the common modifiable maternal factors contributing to macrosomia.

摘要

目的

确定妊娠期糖尿病(GDM)女性巨大儿的患病率、危险因素及妊娠结局。

方法

在这项前瞻性观察研究中,我们纳入了161例诊断为GDM的孕妇的数据。该研究于2020年12月1日至2021年6月30日在沙特阿拉伯海尔市妇幼医院进行。从每位患者处获取有关巨大儿危险因素的数据。对患者进行随访直至婴儿出生。记录有关胎儿巨大儿患病率及其相关结局的数据。

结果

胎儿巨大儿的患病率为19.8%。孕妇肥胖(比值比4.87)、糖尿病控制不佳(比值比3.3)、既往有巨大儿史(比值比2.30)、既往有先天性异常史(比值比7.2)是胎儿巨大儿的重要危险因素。在合并胎儿巨大儿的妊娠中,母婴并发症的患病率较高。与血糖控制理想的GDM患者相比,血糖控制不佳的GDM患者中胎儿巨大儿及其他胎儿并发症的患病率较高。

结论

胎儿巨大儿是GDM患者中的常见并发症。孕妇肥胖和糖尿病控制不佳是导致巨大儿的常见可改变的母体因素。

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