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沙特阿拉伯女性中因肥胖和妊娠期糖尿病导致的妊娠相关并发症。

Pregnancy related complications due to obesity and gestational diabetes mellitus among women in Saudi Arabia.

作者信息

Zahra Aqeela, Hassan Sehar-Un-Nisa, Parveen Nuzhat, Iqbal Naveed, Batool Asma

机构信息

Department of Family and Community Medicine, College of Medicine, University of Ha'il, Saudi Arabia.

Department of Public Health, College of Public Health and Health Informatics, University of Ha'il, Saudi Arabia.

出版信息

Afr J Reprod Health. 2022 Feb;26(2):38-46. doi: 10.29063/ajrh2022/v26i2.4.

Abstract

Gestational Diabetes mellitus (GDM) is one of the major maternal health problems in Middle East countries. In Saudi Arabia, the prevalence rates of GDM fall in the range of 16.2% to 24.2%. The study determined the antenatal complications and adverse pregnancy outcomes associated with GDM among a sample of Obese/GDM and Non-Obese/GDM women. A record based retrospective study was conducted including females who received obstetric care in a tertiary care hospital in Ha'il city of Saudi Arabia from December 2020 to June 2021. We gathered data from the medical records of 376 pregnant females who were registered and delivered at Maternity and Children Hospital (MCH). Multinomial regression analysis was applied to determine independent association of GDM and Obesity with pre-postnatal health outcomes. Out of 376 pregnant women 29.2% were identified as (Non-Obese/Non-GDM); 37.1% of women as having both conditions (GDM/Obesity); 19.2% as (Non-Obese/GDM) and 14.1% as (Obese/Non-GDM). The proportion of underweight and overweight babies were high in women with both conditions (Obese/GDM). Findings from our regression analysis demonstrated that Non-Obese/GDM women were 2.7 times more likely to have high child birthweight (p <0.001) when compared to Non-Obese/Non-GDM. Obese/GDM women were more likely to have low Appearance, Pulse, Grimace, Activity, and Respiration (APGAR) scores (p <0.001) and increase neonatal intensive care unit (NICU) admissions (p<0.01). Healthcare policy makers and professionals should revisit gaps in existing obstetrical care to prevent adverse impact on women and newborn health. Non-Obese women at risk of GDM should also be given due attention for early screening, timely diagnosis, and appropriate pre-postnatal care.

摘要

妊娠糖尿病(GDM)是中东国家主要的孕产妇健康问题之一。在沙特阿拉伯,GDM的患病率在16.2%至24.2%之间。该研究确定了肥胖/GDM和非肥胖/GDM女性样本中与GDM相关的产前并发症和不良妊娠结局。进行了一项基于记录的回顾性研究,纳入了2020年12月至2021年6月在沙特阿拉伯哈伊勒市一家三级护理医院接受产科护理的女性。我们从在妇幼医院(MCH)登记并分娩的376名孕妇的病历中收集了数据。应用多项回归分析来确定GDM和肥胖与产前产后健康结局的独立关联。在376名孕妇中,29.2%被确定为(非肥胖/非GDM);37.1%的女性同时患有这两种疾病(GDM/肥胖);19.2%为(非肥胖/GDM),14.1%为(肥胖/非GDM)。同时患有这两种疾病(肥胖/GDM)的女性中,低体重儿和超重儿的比例较高。我们的回归分析结果表明,与非肥胖/非GDM女性相比,非肥胖/GDM女性分娩时新生儿体重高的可能性高2.7倍(p<0.001)。肥胖/GDM女性的新生儿外观、脉搏、 grimace(对刺激的反应)、活动和呼吸(APGAR)评分较低的可能性更大(p<0.001),且新生儿重症监护病房(NICU)入院率增加(p<0.01)。医疗保健政策制定者和专业人员应重新审视现有产科护理中的差距,以防止对妇女和新生儿健康产生不利影响。有GDM风险的非肥胖女性也应得到应有的关注,以便进行早期筛查、及时诊断和适当的产前产后护理。

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