Xie Dan, Wang Ruimeng, Fu Jinghao, Zhao Zhongxing, Li Min
CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China.
Guangxi Key Laboratory of Agro-Environment and Agro-Product Safety, School of Chemistry and Chemical Engineering, Guangxi University, Nanning, China.
Front Bioeng Biotechnol. 2022 Jun 20;10:921693. doi: 10.3389/fbioe.2022.921693. eCollection 2022.
Surface-enhanced Raman scattering (SERS) is an important and powerful analytical technique in chemical and biochemical analyses. Metal-organic frameworks (MOFs) can effectively capture volatile organic compounds (VOCs) with high adsorption capacity and fast kinetics, and the local surface plasmon resonance characteristics of gold nanoparticles can quickly and effectively distinguish different VOCs by SERS. Combining both, we designed a novel SERS substrate based on embedding gold nanoparticles (AuNPs) within MIL-101(Cr) for the recognition of various VOCs in the gaseous phase. Occupying of AuNPs inside MIL-101(Cr) increased the micropore-specific surface area of AuNPs@MIL-101(Cr), which enabled AuNPs@MIL-101(Cr) to absorb more toluene molecules and consequently realized its high detection sensitivity. The detection limits for toluene, 4-ethylbenzaldehyde, and formaldehyde were down to 6, 5, and 75, ppm respectively. Moreover, this substrate could be used for detecting different VOCs simultaneously. Finally, we discussed the enhancement of AuNPs outside and inside MIL-101(Cr) on the Raman signal.
表面增强拉曼散射（SERS）是化学和生化分析中一种重要且强大的分析技术。金属有机框架（MOF）能够以高吸附容量和快速动力学有效地捕获挥发性有机化合物（VOC），并且金纳米颗粒的局域表面等离子体共振特性可以通过SERS快速有效地区分不同的VOC。将两者结合，我们设计了一种基于将金纳米颗粒（AuNP）嵌入MIL-101（Cr）中的新型SERS基底，用于识别气相中的各种VOC。AuNP在MIL-101（Cr）内部的占据增加了AuNP@MIL-101（Cr）的微孔比表面积，这使得AuNP@MIL-101（Cr）能够吸收更多的甲苯分子，从而实现其高检测灵敏度。甲苯、4-乙基苯甲醛和甲醛的检测限分别低至6、5和75 ppm。此外，该基底可用于同时检测不同的VOC。最后，我们讨论了MIL-101（Cr）外部和内部的AuNP对拉曼信号的增强作用。
