钯-103敷贴近距离放射疗法治疗视网膜母细胞瘤：长期随访
Palladium-103 plaque brachytherapy for retinoblastoma: Long term follow up.
作者信息
Maheshwari Abhilasha, Finger Paul T
机构信息
Department of Ocular Tumor, Orbital Disease and Ophthalmic Radiation Therapy, The New York Eye Cancer Center, 115 East 61st Street, New York City, New York, 10065, USA.
出版信息
Am J Ophthalmol Case Rep. 2022 Jun 23;27:101636. doi: 10.1016/j.ajoc.2022.101636. eCollection 2022 Sep.
PURPOSE
Radiation has been used in the treatment of retinoblastoma. Herein, we present the novel use of palladium-103 plaque brachytherapy as primary treatment.
OBSERVATION
An 8-year-old asymptomatic girl presented was found to have a solitary peripheral retinoblastoma in her right eye. She was treated with primary palladium-103 plaque brachytherapy (47.4 Gray over 5 consecutive days). A secondary, vitreous hemorrhage noted 46 months after irradiation was successfully controlled by laser tumor-demarcation. With 19-years follow up, there has been no clinical scleropathy, or local tumor recurrence. The eye yields 20/20 vision and there has been no systemic metastasis.
CONCLUSION AND IMPORTANCE
Palladium-103 plaque brachytherapy successfully controlled retinoblastoma, while preserving the globe, vision, and life.
目的
放射疗法已用于视网膜母细胞瘤的治疗。在此，我们介绍钯 - 103敷贴近距离放射疗法作为主要治疗方法的新用途。
观察
一名8岁无症状女孩被发现右眼有一个孤立的周边视网膜母细胞瘤。她接受了原发性钯 - 103敷贴近距离放射疗法（连续5天给予47.4戈瑞）。放疗46个月后出现的继发性玻璃体出血通过激光肿瘤划界成功得到控制。经过19年的随访，未出现临床巩膜病变或局部肿瘤复发。患眼视力为20/20，且无全身转移。
结论及重要性
钯 - 103敷贴近距离放射疗法成功控制了视网膜母细胞瘤，同时保留了眼球、视力和生命。
Zotero 插件