Roshanravan Vahid, Soltani Ehsan, Hasanzadeh Haddad Ehsan, Sadeghi Ramin, Sahebkari Azadeh, Mottaghi Mahdi, Aghaee Atena
Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Asia Ocean J Nucl Med Biol. 2022 Spring;10(2):138-141. doi: 10.22038/AOJNMB.2021.59706.1415.
A 53-year-old woman with a plantar malignant melanoma lesion was referred to our tertiary clinic for sentinel lymph node mapping. Lymphoscintigraphy with Tc-Phytate detected ipsilateral inguinal and popliteal sentinel nodes. After total resection of nodes, the pathology report confirmed that all specimens were involved by the tumor. As part of an institutional study evaluating somatostatin receptor avidity of melanoma by Tc-HYNIC-TOC scan, she also underwent a whole-body octreotide scan, which surprisingly showed intense tracer uptake in the right cervical region, confining in SPECT/CT images to a mass at the C2 spinal level, adjacent to the right carotid bifurcation. Neck surgery with gamma probe after injection of another dose of Tc-HYNIC-TOC was performed successfully, and the pathology report was consistent with a carotid body tumor. To best our knowledge, our case is the first one in the literature, which reports an incidental paraganglioma with Tc-HYNIC-TOC scan which resected via radio-guided surgery, again with Tc-HYNIC-TOC tracer.
一名患有足底恶性黑色素瘤病变的53岁女性被转诊至我们的三级诊所进行前哨淋巴结定位。用锝-植酸盐进行的淋巴闪烁显像检测到同侧腹股沟和腘窝前哨淋巴结。在对淋巴结进行全切除后，病理报告证实所有标本均有肿瘤累及。作为一项通过锝-乙二胺四乙酸-奥曲肽扫描评估黑色素瘤生长抑素受体亲和力的机构研究的一部分，她还接受了全身奥曲肽扫描，结果令人惊讶地显示右颈部区域有强烈的示踪剂摄取，在SPECT/CT图像中局限于C2椎体水平的一个肿块，毗邻右颈动脉分叉处。在注射另一剂锝-乙二胺四乙酸-奥曲肽后，成功地使用伽马探针进行了颈部手术，病理报告与颈动脉体瘤相符。据我们所知，我们的病例是文献中首例报告通过锝-乙二胺四乙酸-奥曲肽扫描偶然发现副神经节瘤，并再次使用锝-乙二胺四乙酸-奥曲肽示踪剂通过放射性引导手术切除的病例。
