Kotani Toshiaki, Sakuma Tsuyoshi, Iijima Yasushi, Aoki Yasuchika, Sakashita Kotaro, Okuyama Kohei, Sunami Takahiro, Sato Kosuke, Asada Tomoyuki, Akazawa Tsutomu, Inage Kazuhide, Shiga Yasuhiro, Hozumi Takashi, Minami Shohei, Ohtori Seiji
Department of Orthopedic Surgery, Seirei Sakura Citizen Hospital, Sakura, Japan.
Department of Orthopedic Surgery, Eastern Chiba Medical Center, Chiba, Japan.
Spine Surg Relat Res. 2021 Dec 14;6(3):247-251. doi: 10.22603/ssrr.2021-0176. eCollection 2022.
Although lateral vertebral translation is associated with inducing curve progression and pain, no study has analyzed risk factors for lateral slip in patients with residual adolescent idiopathic scoliosis (AIS). This study aimed to investigate risk factors for lateral slip in patients with residual AIS.
We included 42 preoperative patients with residual AIS with a thoracolumbar/lumbar (TL/L) curve (3 male, 39 female; age 41.9±18.2 years, TL/L Cobb angle 55.5±10.0°). All patients were >20 years and had been diagnosed with AIS during their adolescence. Lateral slip was defined as more than a 6-mm slip on coronal CT images.
Patients were divided into slip (n=22) and nonslip (n=20) groups. Significant differences were observed in age, TL/L Cobb angle, TL/L curve flexibility, lumbar lordosis, thoracolumbar kyphosis, apical vertebral rotation, apical vertebral translation, and L3 and L4 tilt between the groups. Multivariate analyses and receiver operating characteristic curves found that only older age was a significant risk factor for lateral slip (odds ratio: 1.214; 95% confidence interval: 1.047-1.407; =0.010), with a cutoff value of 37 years old.
Older age, especially >37 years, is a risk factor for lateral slip in patients with residual AIS. These findings suggest that surgery for residual AIS should be considered before patients are in their mid-30s to avoid lateral translation.
尽管椎体侧方移位与脊柱侧弯进展及疼痛相关,但尚无研究分析残留青少年特发性脊柱侧弯(AIS)患者发生侧方滑脱的危险因素。本研究旨在调查残留AIS患者发生侧方滑脱的危险因素。
我们纳入了42例术前残留AIS且存在胸腰段/腰段(TL/L)侧弯的患者(男性3例,女性39例;年龄41.9±18.2岁,TL/L Cobb角55.5±10.0°)。所有患者年龄均大于20岁,且在青少年时期被诊断为AIS。侧方滑脱定义为冠状位CT图像上移位超过6mm。
患者被分为滑脱组(n=22)和非滑脱组(n=20)。两组在年龄、TL/L Cobb角、TL/L侧弯柔韧性、腰椎前凸、胸腰段后凸、顶椎旋转、顶椎移位以及L3和L4倾斜度方面存在显著差异。多因素分析和受试者工作特征曲线发现,只有年龄较大是侧方滑脱的显著危险因素(比值比:1.214;95%置信区间:1.047 - 1.407;P=0.010),临界值为37岁。
年龄较大,尤其是大于37岁,是残留AIS患者发生侧方滑脱的危险因素。这些发现表明,对于残留AIS患者,应在其35岁中期之前考虑手术,以避免侧方移位。