Yoon Jennifer, Hu Steve, Phillips Daniel, Fathi Amir, Ameer Adnan
Department of Internal Medicine, University of California, Fresno, CA, USA.
Department of Gastroenterology and Hepatology, University of California, Fresno, CA, USA.
Case Reports Hepatol. 2022 Jun 28;2022:5765116. doi: 10.1155/2022/5765116. eCollection 2022.
Immunoglobulin G subclass 4 (IgG-4)-related disease (IgG4-RD) is an uncommon immune-mediated, fibro-inflammatory disease which has garnered recognition as a systemic condition. One manifestation of the disease in the hepatobiliary system is the development of hepatic inflammatory pseudotumors. These benign tumors are often misdiagnosed as malignant tumors and undergo unnecessary hepatic resections. We present a case of IgG4-related hepatic inflammatory pseudotumor (IPT) mimicking a Klatskin tumor. A high degree of clinical suspicion and extensive workup is imperative in reaching the correct diagnosis. IgG4-related inflammatory pseudotumor is a rare entity, but an important consideration in evaluating hepatic tumors.
免疫球蛋白G4（IgG-4）相关疾病（IgG4-RD）是一种罕见的免疫介导的纤维炎症性疾病，已被公认为一种全身性疾病。该疾病在肝胆系统的一种表现是肝脏炎性假瘤的形成。这些良性肿瘤常被误诊为恶性肿瘤并接受不必要的肝脏切除术。我们报告一例酷似肝门部胆管癌的IgG4相关性肝脏炎性假瘤（IPT）病例。高度的临床怀疑和全面的检查对于做出正确诊断至关重要。IgG4相关性炎性假瘤是一种罕见的疾病，但在评估肝脏肿瘤时是一个重要的考虑因素。
