Greco Elena, Elmandouh Omar, Desai Amit, Bhatt Alok, Vibhute Prasanna, Aggarwal Amit
Mayo Clinic, 4500 San Pablo Road, Jacksonville, Fl 32224 USA.
Radiol Case Rep. 2022 Jun 27;17(9):3157-3161. doi: 10.1016/j.radcr.2022.05.082. eCollection 2022 Sep.
Calcifying pseudoneoplasms of the neuraxis (CAPNON) are very rare intracranial lesions with less than 50 cases reported in literature. These are non-neoplastic in etiology and despite having unique imaging characteristics, are often misdiagnosed as a neoplastic condition like meningioma, chordoma and gliomas. These do not have any predilection for any age, gender or intracranial location and can be seen in a wide range of age groups. Despite having an imaging overlap with neoplastic conditions, CAPNONs have classic histopathologic findings including chondromyxoid matrix, palisading spindle cells and calcific or ossific metaplasia. As more cases are being described in literature the imaging features are also being better defined. We discuss the clinical, imaging and histopathological findings of 2 cases of CAPNON mimicking posterior fossa meningioma and glial neoplasm.
神经轴钙化性假瘤（CAPNON）是非常罕见的颅内病变，文献报道不足50例。其病因是非肿瘤性的，尽管具有独特的影像学特征，但常被误诊为脑膜瘤、脊索瘤和胶质瘤等肿瘤性疾病。这些病变对任何年龄、性别或颅内位置均无偏好，可见于广泛的年龄组。尽管CAPNON在影像学上与肿瘤性疾病有重叠，但具有典型的组织病理学表现，包括软骨黏液样基质、栅栏状梭形细胞以及钙化或骨化生。随着文献中描述的病例增多，其影像学特征也得到了更好的界定。我们讨论了2例酷似后颅窝脑膜瘤和神经胶质瘤的CAPNON的临床、影像学和组织病理学表现。
