Thakur Bhaskar, Riches Simon, Costello Angela, Aizpurua Miren, Bodi Istvan, Ashkan Keyoumars
Neurosurgery, King's College Hospital, London, GBR.
Psychology, King's College Hospital, London, GBR.
Cureus. 2019 Jan 29;11(1):e3982. doi: 10.7759/cureus.3982.
Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare tumours. We describe a CAPNON in the posterior fossa and its associated neuropsychological sequelae to provide further evidence for the role of cerebellum in cognitive function. We report the clinical details, imaging, pre-operative neuropsychological assessment, histological features and management of a patient with such a tumour in the posterior fossa location. Detailed pre-operative neuropsychological assessment identified a number of cognitive deficits that had the hallmarks of dysexecutive syndrome. Post-surgery, there was considerable improvement, most notably on processing speed tasks and selected executive tests. This rare case provides further evidence for the role of cerebellum in cognitive function.
神经轴钙化性假瘤（CAPNON）是罕见肿瘤。我们描述了一例后颅窝的CAPNON及其相关的神经心理学后遗症，以进一步证明小脑在认知功能中的作用。我们报告了一名后颅窝部位患有此类肿瘤患者的临床细节、影像学表现、术前神经心理学评估、组织学特征及治疗情况。详细的术前神经心理学评估发现了一些具有执行功能障碍综合征特征的认知缺陷。术后有显著改善，最明显的是在处理速度任务和特定执行测试方面。这个罕见病例为小脑在认知功能中的作用提供了进一步证据。
