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巴西绝经期女性特征分析:巴西绝经研究结果。

Profile of Brazilian climacteric women: results from the Brazilian Menopause Study.

机构信息

Obstetric and Gynecology Department, Faculdade de Medicina do ABC, Santo André, Brazil.

Obstetric and Gynecology Department, Faculdade de Medicina de Jundiaí, Jundiaí, Brazil.

出版信息

Climacteric. 2022 Oct;25(5):523-529. doi: 10.1080/13697137.2022.2088276. Epub 2022 Jul 8.

DOI:10.1080/13697137.2022.2088276
PMID:35801642
Abstract

OBJECTIVE

This study aims to understand the epidemiological characteristics of Brazilian menopausal women, and their view on menopause hormone therapy (MHT).

METHODS

A national cross-sectional study with 1500 women between 45 and 65 years old was carried out through questionnaires.

RESULTS

The overall median age of participants was 52 [47-56] years, and 55 [52-59] years for the postmenopausal subgroup. Menstrual irregularity started at median age 46 [44-49] years. Median menopause age was 48 [45-51] years with no differences between socioeconomic classes. The prevalence of any climacteric symptoms was 87.9% and hot flashes started at median age 47 [45-50] years. Among women in menopause/menopausal transition, 52.1% received any medical prescription, and MHT was recommended for 22.3%. Among those who started MHT, 45.4% were still using the treatment and the median duration of use was 8 months, but different among socioeconomic classes (24 months for class A against 3 months for class D/E).

CONCLUSIONS

In this first Brazilian national population-based study on menopause and MHT, it was observed that, in spite of being symptomatic when entering menopause around 48 years of age, only a small part of Brazilian women started MHT and the median duration of treatment was less than 1 year, but the duration was higher for higher socioeconomic class.

摘要

目的

本研究旨在了解巴西绝经女性的流行病学特征及其对绝经激素治疗(MHT)的看法。

方法

通过问卷调查,对 1500 名年龄在 45 至 65 岁之间的巴西女性进行了一项全国性的横断面研究。

结果

参与者的总体中位年龄为 52 岁[47-56],绝经后亚组的中位年龄为 55 岁[52-59]。月经不规则开始于中位年龄 46 岁[44-49]。中位绝经年龄为 48 岁[45-51],社会经济阶层之间无差异。任何更年期症状的患病率为 87.9%,热潮红开始于中位年龄 47 岁[45-50]。在处于绝经/绝经过渡期的女性中,有 52.1%接受了任何药物治疗,有 22.3%推荐使用 MHT。在开始使用 MHT 的女性中,有 45.4%仍在使用该治疗方法,中位使用时间为 8 个月,但在社会经济阶层中存在差异(A 类为 24 个月,D/E 类为 3 个月)。

结论

在这项巴西首次基于全国人口的绝经和 MHT 研究中,尽管在 48 岁左右绝经时出现症状,但只有一小部分巴西女性开始使用 MHT,治疗的中位持续时间不到 1 年,但社会经济阶层越高,持续时间越长。

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