Department of General Surgery, The Affiliated People's Hospital of Ningbo University, Ningbo, Zhejiang, China.
Medicine (Baltimore). 2022 Jul 8;101(27):e29899. doi: 10.1097/MD.0000000000029899.
Totally implantable venous access port (TIVAP) has become an important infusion channel for children who need chemotherapy. With the popularization of TIVAP, its related complications have gradually received clinical attention. However, there are few studies on the complications of TIVAP in children. Therefore, this study intends to analyze the risk factors of complications in children's infusion port, so as to provide basis for guiding clinical prevention and intervention. This paper retrospectively analyzed 182 children who received TIVAP implantation in our hospital from January 2018 to January 2021. According to the demographic data, basic disease status and operation related data obtained through Hospital Information System and manual follow-up, the complications and related influencing factors after implantation and implantation were summarized and analyzed. SPSS software was used to analyze the influencing factors between the complication group and the control group. There were 182 cases of children implanted in intravenous infusion port, of which 71 cases had complications, infection was the most common complication in 50 cases, followed by catheter blockage in 23 cases. Among the infection factors, catheter-related blood stream infection accounted for the highest proportion in 31 cases (17.0%), and Staphylococcus epidermidis was the most common pathogen. A total of 19 cases were pulled out early, and the unplanned pullout rate of catheter-related blood stream infection was the highest. In the analysis of influencing factors, age had significant differences in catheter-related infection, all complications and no complications (P < .05). The overall incidence of complications in the use of TIVAP in children with chemotherapy is high, and infection is the most common complication, among which catheter-related blood stream infection is the most common cause of unplanned pullout. Lower age may be associated with a higher incidence of complications.
完全植入式静脉输液港(TIVAP)已成为需要化疗的儿童重要的输液通道。随着 TIVAP 的普及,其相关并发症逐渐受到临床关注。然而,关于儿童 TIVAP 并发症的研究较少。因此,本研究旨在分析儿童输液港并发症的危险因素,为指导临床预防和干预提供依据。本研究回顾性分析了 2018 年 1 月至 2021 年 1 月我院收治的 182 例行 TIVAP 植入术的患儿。根据从医院信息系统和人工随访中获得的人口统计学数据、基本疾病状况和手术相关数据,总结和分析了植入和植入后的并发症及相关影响因素。采用 SPSS 软件分析并发症组和对照组之间的影响因素。共 182 例儿童植入静脉输液港,其中 71 例发生并发症,感染最为常见,共 50 例,其次是导管堵塞 23 例。在感染因素中,导管相关性血流感染占比最高,共 31 例(17.0%),最常见的病原体为表皮葡萄球菌。共 19 例提前拔出,导管相关性血流感染的计划性拔出率最高。在影响因素分析中,年龄在导管相关性感染、所有并发症和无并发症中差异均有统计学意义(P<0.05)。儿童化疗中使用 TIVAP 的总体并发症发生率较高,感染是最常见的并发症,其中导管相关性血流感染是计划性拔出的最常见原因。较低的年龄可能与更高的并发症发生率相关。