Department of Chemistry, Portland State University, Portland, Oregon 97207, United States.
FloraWorks Holdings, Inc., Milwaukie, Oregon 97222, United States.
Chem Res Toxicol. 2022 Jul 18;35(7):1202-1205. doi: 10.1021/acs.chemrestox.2c00170. Epub 2022 Jul 8.
Δ-THC acetate is a relatively new psychoactive cannabis product that is available online and in vape shops across the United States since it is currently largely unregulated. Because it contains a similar substructure to vitamin E acetate, which has been shown to form the poison gas ketene during vaping, we investigated potential ketene formation from Δ-THC acetate, as well as two other cannabinoids acetates, CBN acetate and CBD acetate, under vaping conditions. Ketene was consistently observed in vaped condensates from all three cannabinoid acetates as well as from a commercial Δ-THC acetate product purchased online.
Δ-THC 醋酸酯是一种相对较新的精神活性大麻产品，由于目前尚未得到广泛监管，因此可在美国各地的在线商店和蒸气烟商店购买。由于它含有与维生素 E 醋酸酯相似的结构，而维生素 E 醋酸酯在蒸气烟中已被证明会形成毒瓦斯丙烯醛，因此我们研究了在蒸气烟条件下，Δ-THC 醋酸酯以及另外两种大麻素醋酸酯，即 CBN 醋酸酯和 CBD 醋酸酯，是否有可能形成丙烯醛。在所有三种大麻素醋酸酯以及从网上购买的一种商业用 Δ-THC 醋酸酯产品的蒸气冷凝物中，都一致观察到丙烯醛的存在。
