Department of Orthopedic Surgery, Mayo Clinic, Jacksonville, Florida.
Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
J Arthroplasty. 2022 Dec;37(12):2347-2352. doi: 10.1016/j.arth.2022.06.026. Epub 2022 Jul 6.
For patients who have a history of cerebrovascular accident (CVA) with neurological sequelae undergoing primary total hip arthroplasty (THA) and total knee arthroplasty (TKA), we sought to determine mortality rate, implant survivorship, complications, and clinical outcomes.
Our total joint registry identified CVA sequelae patients undergoing primary THA (n = 42 with 25 on affected hip) and TKA (n = 56 with 34 on affected knee). Patients were 1:2 matched based upon age, sex, body mass index, and surgical year to a non-CVA cohort. Mortality and implant survivorship were evaluated via Kaplan-Meier methods. Clinical outcomes were assessed via Harris Hip scores or Knee Society scores . Mean follow-up was 5 years (range, 2-12).
For CVA sequelae and non-CVA patients, respectively, the 5-year patient survivorship was 69 versus 89% after THA (HR = 2.5; P = .006) and 56 versus 90% after TKA (HR = 2.4, P = .003). No significant difference was noted between groups in implant survivorship free from any reoperation after THA (P > .2) and TKA (P > .6). Postoperative CVA occurred at an equal rate in CVA sequelae and non-CVA patients after TKA (1.8%); none after THA in either group. The magnitude of change in Harris Hip scores (P = .7) and Knee Society scores (P = .7) were similar for CVA sequelae and non-CVA patients.
Complications, including the risk of postoperative CVA, implant survivorship, and outcome score improvement are similar for CVA sequelae and non-CVA patients. A 2.5-fold increased risk of death at a mean of 5 years after primary THA or TKA exist for CVA sequelae patients.
对于患有脑血管意外(CVA)并有神经后遗症的患者,行初次全髋关节置换术(THA)和全膝关节置换术(TKA),我们旨在确定死亡率、假体存活率、并发症和临床结果。
我们的关节置换登记处确定了患有 CVA 后遗症的初次行 THA(42 例,其中 25 例在受累髋关节)和 TKA(56 例,其中 34 例在受累膝关节)的患者。根据年龄、性别、体重指数和手术年份,将 CVA 组患者与非 CVA 组患者进行 1:2 配对。通过 Kaplan-Meier 方法评估死亡率和假体存活率。通过 Harris 髋关节评分或膝关节协会评分评估临床结果。平均随访时间为 5 年(范围,2-12 年)。
对于 CVA 后遗症和非 CVA 患者,THA 后 5 年患者存活率分别为 69%和 89%(HR=2.5;P=0.006),TKA 后分别为 56%和 90%(HR=2.4,P=0.003)。THA (P>0.2)和 TKA (P>0.6)后无任何再手术的假体存活率在两组之间无显著差异。CVA 后遗症和非 CVA 患者 TKA 后发生 CVA 的比例相同(1.8%);两组均无 THA 后发生 CVA。Harris 髋关节评分(P=0.7)和膝关节协会评分(P=0.7)的变化幅度在 CVA 后遗症和非 CVA 患者中相似。
并发症,包括术后 CVA 的风险、假体存活率和结局评分改善,在 CVA 后遗症和非 CVA 患者中相似。CVA 后遗症患者初次 THA 或 TKA 后 5 年的死亡风险增加 2.5 倍。