Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA.
Exponent Inc, Philadelphia, PA.
J Arthroplasty. 2018 Jul;33(7):2070-2074.e1. doi: 10.1016/j.arth.2018.01.064. Epub 2018 Feb 8.
The purpose of this study is to evaluate the impact of prior bariatric surgery on survivorship, outcome, and complications following primary total hip arthroplasty (THA)/total knee arthroplasty (TKA).
Using the Medicare 5% part B data from 1999 to 2012, we analyzed patients who underwent primary THA (n = 47,895) and primary TKA (n = 86,609). Patients with prior bariatric surgery before arthroplasty were compared to patients with other common metabolic conditions. Kaplan-Meier risk of revision THA/TKA for those with and without bariatric surgery and each of the metabolic bone conditions was calculated. The risk for infection was also evaluated. Regression analysis was used to determine the relative risk of revision at various time intervals for those with and without each of the metabolic conditions. Analysis was also adjusted for the metabolic conditions, age, gender, socioeconomic status, and Charlson comorbidity index.
The prevalence of patients with prior bariatric surgery within 24 months of primary THA/TKA was 0.1%. Benchmarked against other common chronic metabolic conditions, bariatric surgery prior to THA was not associated with an increased risk for revision surgery at all measured intervals but positively correlated with increased risk for developing infections. Conversely, patients undergoing primary TKA following bariatric surgery were at increased risk for revision compared to controls but not at increased risk for infection.
The impact of bariatric surgery prior to elective THA/TKA remains unclear. These patients remain at increased risk for infections following THA and revisions following TKA.
本研究旨在评估肥胖症手术史对初次全髋关节置换术(THA)/全膝关节置换术(TKA)后生存率、结果和并发症的影响。
利用 1999 年至 2012 年 Medicare 5%部分 B 数据,我们分析了接受初次 THA(n=47895)和初次 TKA(n=86609)的患者。将接受过关节置换术前肥胖症手术的患者与其他常见代谢性疾病的患者进行比较。计算有和无肥胖症手术的患者以及每种代谢性骨病的 Kaplan-Meier 风险。还评估了感染风险。使用回归分析确定了有和无每种代谢性疾病的患者在各个时间间隔修正的相对风险。分析还针对代谢性疾病、年龄、性别、社会经济地位和 Charlson 合并症指数进行了调整。
初次 THA/TKA 前 24 个月内有肥胖症手术史的患者比例为 0.1%。与其他常见慢性代谢性疾病相比,THA 前的肥胖症手术史与所有测量间隔的翻修手术风险增加无关,但与感染风险增加呈正相关。相反,接受过肥胖症手术的患者在初次 TKA 后翻修的风险增加,但感染风险没有增加。
肥胖症手术对择期 THA/TKA 的影响仍不清楚。这些患者在接受 THA 后和接受 TKA 后翻修时仍有更高的感染风险。