Speciality of Addiction Medicine, Central Clinical School, Faculty of Medicine and Health, The University of Sydney, NSW, 2006, Australia.
Drug Health Services, Royal Prince Alfred Hospital, Sydney Local Health District, Camperdown, NSW, 2050, Australia.
BMC Prim Care. 2022 Jul 8;23(1):171. doi: 10.1186/s12875-022-01783-y.
Prescribed opioid doses > 100 mg oral morphine equivalent (OME) and/or co-prescribing of sedating psychoactive medications increase the risk of unintentional fatal overdose. We describe general practice encounters where opioids are prescribed and examine high-risk opioid prescribing.
The 2006-2016 BEACH study data, a rolling national cross-sectional survey of randomly selected GPs, was analysed.
Opioid prescribing increased 2006-2007 to 2015-2016, however, this plateaued across the latter half-decade. From 2012-2016 3,897 GPs recorded 389,700 encounters and at least one opioid was prescribed at 5.2%. Opioid encounters more likely involved males, those 45-64 years, concession card holders and the socioeconomically disadvantaged. GPs more likely to prescribe opioids were 55 years or older, male, Australian graduates, and in regional and remote areas. The most common problems managed with opioids involved chronic non-cancer pain. One-in-ten opioid prescribing episodes involved high-risk doses and 11% involved co-prescription of sedating psychoactive medications. Over one-third of GPs provided other (non-pharmacological) interventions at encounters with opioid prescriptions.
Only 5% of GP encounters involved an opioid prescription. Of concern, were: prescribing for chronic non-cancer pain, potentially high-risk opioid encounters where > 100 OME daily dose was prescribed, and/or there was co-prescription of sedating psychoactive medication. However, approximately one-in-three opioid prescribing encounters involved non-pharmacological interventions.
处方阿片类药物剂量> 100 毫克口服吗啡当量(OME)和/或同时开具镇静性精神活性药物会增加意外致命性过量用药的风险。我们描述了开具阿片类药物的一般实践情况,并检查了高风险阿片类药物的开具情况。
对 2006-2016 年 BEACH 研究数据进行了分析,这是一项针对随机选择的全科医生的滚动式全国横断面调查。
2006-2007 年阿片类药物的处方量增加,但在过去五年中趋于平稳。2012-2016 年,3897 名全科医生记录了 389700 次就诊,其中至少有 5.2%的就诊者开具了阿片类药物。阿片类药物的就诊者更可能是男性、45-64 岁、优惠卡持有者和社会经济地位较低的人群。更有可能开具阿片类药物的全科医生年龄在 55 岁或以上、男性、澳大利亚毕业、在地区和偏远地区工作。最常见的用阿片类药物治疗的问题涉及慢性非癌症疼痛。十分之一的阿片类药物处方涉及高剂量,11%的处方涉及同时开具镇静性精神活性药物。三分之一以上的全科医生在开具阿片类药物处方的就诊时提供了其他(非药物)干预措施。
只有 5%的全科医生就诊涉及阿片类药物处方。令人担忧的是,为慢性非癌症疼痛开具处方、处方中每日 OME 剂量> 100 的潜在高风险阿片类药物处方,和/或同时开具镇静性精神活性药物。然而,大约三分之一的阿片类药物处方涉及非药物干预措施。