• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

感染性心内膜炎导致乳头肌断裂引起的急性二尖瓣反流。

Acute mitral valve regurgitation secondary to papillary muscle rupture due to infective endocarditis.

机构信息

Department of General Surgery, Houston Methodist Hospital, Houston, TX, USA.

DeBakey Heart and Vascular Center, Houston Methodist Hospital, 6550 Fannin St, Smith Tower Suite 1401, Houston, TX, 77030, USA.

出版信息

J Cardiothorac Surg. 2022 Jul 8;17(1):173. doi: 10.1186/s13019-022-01854-2.

DOI:10.1186/s13019-022-01854-2
PMID:35804449
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9270734/
Abstract

BACKGROUND

Papillary muscle rupture due to infective endocarditis is a rare event and proper management of this condition has not been described in the literature. Our case aims to shed light on treatment strategies for these patients using the current guidelines.

CASE PRESENTATION

This case presents a 58-year-old male with acute heart failure secondary to papillary muscle rupture. He underwent an en bloc resection of his mitral valve with a bioprosthetic valve replacement. Specimen pathology later showed necrotic papillary muscle due to infective endocarditis. The patient was further treated with antibiotic therapy. He recovered well post-operatively and continued to do well after discharge.

CONCLUSION

In patients who present with papillary muscle rupture secondary to infective endocarditis, clinical symptoms should drive the treatment strategy. Despite the etiology, early mitral valve surgery remains treatment of choice for patients who have papillary muscle rupture leading to acute heart failure. Culture-guided prolonged antibiotic treatment is vital in this category of patients, especially those who have a prosthetic valve implanted.

摘要

背景

感染性心内膜炎导致的乳头肌破裂是一种罕见的情况,目前文献中并未描述这种情况下的适当处理方法。本病例旨在使用现有指南阐明此类患者的治疗策略。

病例介绍

本病例为 58 岁男性,因乳头肌破裂导致急性心力衰竭。他接受了二尖瓣整块切除术和生物瓣置换术。随后的标本病理学检查显示,乳头肌因感染性心内膜炎而坏死。患者进一步接受了抗生素治疗。术后恢复良好,出院后情况也一直良好。

结论

对于因感染性心内膜炎导致乳头肌破裂的患者,临床症状应指导治疗策略。尽管病因不同,但对于因乳头肌破裂导致急性心力衰竭的患者,早期二尖瓣手术仍然是治疗的首选方法。对于这一类患者,包括植入了人工瓣膜的患者,基于培养的延长抗生素治疗至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fff/9270734/0b2912082383/13019_2022_1854_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fff/9270734/93576d5dcf58/13019_2022_1854_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fff/9270734/b88955176eb4/13019_2022_1854_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fff/9270734/0b2912082383/13019_2022_1854_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fff/9270734/93576d5dcf58/13019_2022_1854_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fff/9270734/b88955176eb4/13019_2022_1854_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fff/9270734/0b2912082383/13019_2022_1854_Fig3_HTML.jpg

相似文献

1
Acute mitral valve regurgitation secondary to papillary muscle rupture due to infective endocarditis.感染性心内膜炎导致乳头肌断裂引起的急性二尖瓣反流。
J Cardiothorac Surg. 2022 Jul 8;17(1):173. doi: 10.1186/s13019-022-01854-2.
2
Outcomes of emergency or urgent mitral valve repair in patients with papillary muscle rupture and active infective endocarditis.乳头肌破裂和活动性感染性心内膜炎患者急诊或紧急二尖瓣修复的结果。
Asian Cardiovasc Thorac Ann. 2020 Sep;28(7):390-397. doi: 10.1177/0218492320957131. Epub 2020 Sep 16.
3
Anterolateral papillary muscle rupture in Staphylococcus aureus endocarditis due to direct bacterial invasion of papillary muscle.金黄色葡萄球菌心内膜炎中因细菌直接侵袭乳头肌导致前外侧乳头肌破裂。
Echocardiography. 2017 Sep;34(9):1382-1384. doi: 10.1111/echo.13640. Epub 2017 Jul 28.
4
[A case report of infective endocarditis with total rupture of the posterior papillary muscle after aortic valve replacement].[主动脉瓣置换术后感染性心内膜炎合并后乳头肌完全断裂1例报告]
Kyobu Geka. 1998 Dec;51(13):1120-2.
5
[Successful surgical treatment in a case of complete rupture of the posterior papillary muscle of the mitral valve caused by infective endocarditis].[感染性心内膜炎致二尖瓣后乳头肌完全断裂一例的成功外科治疗]
Nihon Kyobu Geka Gakkai Zasshi. 1994 Jul;42(7):1101-4.
6
[A case of infective endocarditis with subtotal rupture of the posterior papillary muscle].[1例伴有后乳头肌次全破裂的感染性心内膜炎]
Kyobu Geka. 1995 Jun;48(6):487-90.
7
Indications for surgical replacement of the mitral valve. With particular reference to common and uncommon causes of mitral regurgitation.二尖瓣手术置换的适应症。特别提及二尖瓣反流的常见和不常见原因。
Am J Cardiol. 1979 Jul;44(1):148-57. doi: 10.1016/0002-9149(79)90264-9.
8
Papillary muscle rupture following routine aortic valve replacement.常规主动脉瓣置换术后乳头肌破裂
J Card Surg. 2019 Dec;34(12):1667-1669. doi: 10.1111/jocs.14247. Epub 2019 Sep 2.
9
Acute mitral valve regurgitation due to complete rupture of anterior papillary muscle mimicking mitral valve vegetation.因前乳头肌完全断裂导致的急性二尖瓣反流,酷似二尖瓣赘生物。
Ann Thorac Cardiovasc Surg. 2011;17(1):81-5. doi: 10.5761/atcs.cr.08.01384.
10
[A case of mitral regurgitation due to partial papillary muscle rupture whose etiology was unknown].一例病因不明的部分乳头肌破裂所致二尖瓣反流病例
Kyobu Geka. 1995 Jan;48(1):80-3.

引用本文的文献

1
Clinical outcomes of transcatheter edge-to-edge repair in patients with acute mitral regurgitation complicated by cardiogenic shock: a systematic review and meta-analysis.经导管缘对缘修复术治疗急性二尖瓣反流合并心源性休克患者的临床结局:一项系统评价和荟萃分析
BMC Cardiovasc Disord. 2025 May 19;25(1):380. doi: 10.1186/s12872-025-04844-z.
2
Papillary Muscle Rupture in the Setting of Endocarditis.心内膜炎合并乳头肌断裂。
J Investig Med High Impact Case Rep. 2024 Jan-Dec;12:23247096241300912. doi: 10.1177/23247096241300912.

本文引用的文献

1
Clinical and Economic Burden of Hospitalizations for Infective Endocarditis in the United States.美国因感染性心内膜炎住院的临床和经济负担。
Mayo Clin Proc. 2020 May;95(5):858-866. doi: 10.1016/j.mayocp.2019.08.023. Epub 2020 Jan 3.
2
Bioprosthetic Versus Mechanical Valve Replacement for Infective Endocarditis: Focus on Recurrence Rates.生物瓣与机械瓣在感染性心内膜炎中的置换:关注复发率。
Ann Thorac Surg. 2018 Jul;106(1):99-106. doi: 10.1016/j.athoracsur.2017.12.046. Epub 2018 Feb 13.
3
2017 ESC/EACTS Guidelines for the management of valvular heart disease.
2017年欧洲心脏病学会/欧洲心胸外科学会瓣膜性心脏病管理指南。
Eur Heart J. 2017 Sep 21;38(36):2739-2791. doi: 10.1093/eurheartj/ehx391.
4
Trends and Patterns of Geographic Variation in Cardiovascular Mortality Among US Counties, 1980-2014.1980 - 2014年美国各县心血管疾病死亡率的地理差异趋势与模式
JAMA. 2017 May 16;317(19):1976-1992. doi: 10.1001/jama.2017.4150.
5
2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.2017年美国心脏协会/美国心脏病学会对2014年《美国心脏协会/美国心脏病学会瓣膜性心脏病患者管理指南》的重点更新:美国心脏病学会/美国心脏协会临床实践指南工作组报告
J Am Coll Cardiol. 2017 Jul 11;70(2):252-289. doi: 10.1016/j.jacc.2017.03.011. Epub 2017 Mar 15.
6
[2015 ESC Guidelines for the management of infective endocarditis. The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC)].[2015年欧洲心脏病学会(ESC)感染性心内膜炎管理指南。欧洲心脏病学会(ESC)感染性心内膜炎管理工作组]
G Ital Cardiol (Rome). 2016 Apr;17(4):277-319. doi: 10.1714/2214.23904.
7
Early versus late surgical intervention or medical management for infective endocarditis: a systematic review and meta-analysis.感染性心内膜炎的早期与晚期手术干预或药物治疗:一项系统评价和荟萃分析
Heart. 2016 Jun 15;102(12):950-7. doi: 10.1136/heartjnl-2015-308589. Epub 2016 Feb 11.