Ren Jiawei, Gao Xinbo, Chen Liming, Lin Huishan, Liu Yao, Zhou Yuying, Liao Yunru, Xie Chunzi, Zuo Chengguo, Lin Mingkai
State Key Laboratory of Ophthalmology, Guangzhou 510060, China.
Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
J Clin Med. 2022 Jun 27;11(13):3696. doi: 10.3390/jcm11133696.
Background: The imaging and analysis of the ciliary body (CB) are valuable in many potential clinical applications. This study aims to demonstrate the anatomy characteristics of CB using radial and transverse imaging of ultrasound biometric microscopy (UBM) in healthy Chinese subjects, and to explore the determining factors. Methods: Fifty-four eyes of 30 healthy Chinese subjects were evaluated. Clinical data, including age, body mass index (BMI), intraocular pressure (IOP), axial length (AL), and lens thickness (LT), were collected. Radial and transverse UBM measurements of the ciliary body were performed. Anterior chamber depth (ACD), ciliary sulcus diameter (CSD), ciliary process length (CPL), ciliary process density (CPD), ciliary process area (CPA), ciliary muscle area (CMA), ciliary body area (CBA), ciliary body thickness (CBT0, CBT1, and CBTmax), anterior placement of ciliary body (APCB), and trabecular-ciliary angle (TCA) of four (superior, nasal, inferior, and temporal) quadrants were measured. Results: The average CPL was 0.513 ± 0.074 mm, and the average CPA was 0.890 ± 0.141 mm2. CPL and CPA tended to be longer and larger in the superior quadrant (p < 0.001) than in the other three quadrants. Average CPL was significantly correlated with AL (r = 0.535, p < 0.001), ACD (r = 0.511, p < 0.001), and LT (r = −0.512, p < 0.001). Intraclass correlation coefficient (ICC) scores were high for CPL (0.979), CPD (0.992), CPA (0.966), CMA (0.963), and CBA (0.951). Conclusions: In healthy Chinese subjects, CPL was greatest in the superior quadrant, followed by the inferior, temporal, and nasal quadrants, and CPA was largest in the superior quadrant, followed by the tempdoral, inferior, and nasal quadrants. Transverse UBM images can be used to measure the anatomy of the ciliary process with relatively good repeatability and reliability.
睫状体（CB）的成像与分析在许多潜在临床应用中具有重要价值。本研究旨在利用超声生物显微镜（UBM）的径向和横向成像展示健康中国受试者睫状体的解剖特征，并探索其决定因素。方法：对30名健康中国受试者的54只眼进行评估。收集临床数据，包括年龄、体重指数（BMI）、眼压（IOP）、眼轴长度（AL）和晶状体厚度（LT）。对睫状体进行UBM径向和横向测量。测量四个象限（上方、鼻侧、下方和颞侧）的前房深度（ACD）、睫状沟直径（CSD）、睫状突长度（CPL）、睫状突密度（CPD）、睫状突面积（CPA）、睫状肌面积（CMA）、睫状体面积（CBA）、睫状体厚度（CBT0、CBT1和CBTmax）、睫状体前部位置（APCB）以及小梁-睫状体角（TCA）。结果：平均CPL为0.513±0.074mm，平均CPA为0.890±0.141mm²。上方象限的CPL和CPA往往比其他三个象限更长、更大（p<0.001）。平均CPL与AL（r = 0.535，p<0.001）、ACD（r = 0.511，p<0.001）和LT（r = -0.512，p<0.001）显著相关。CPL（0.979）、CPD（0.992）、CPA（0.966）、CMA（0.963）和CBA（0.951）的组内相关系数（ICC）得分较高。结论：在健康中国受试者中，上方象限的CPL最大，其次是下方、颞侧和鼻侧象限；上方象限的CPA最大，其次是颞侧、下方和鼻侧象限。横向UBM图像可用于测量睫状突的解剖结构，具有相对较好的重复性和可靠性。
