School of Pharmacy, Jiangxi Science and Technology Normal University, Nanchang 330013, China.
School of Chemistry and Chemical Engineering, Jiangxi Science and Technology Normal University, Nanchang 330013, China.
Molecules. 2022 Jul 4;27(13):4294. doi: 10.3390/molecules27134294.
In view of that conjugated polymers (CPs) are an attractive option for constructing high-sensitive CrO sensors but suffer from lacking a general design strategy, we first proposed a rational structure design of CPs to tailor their sensing properties while validating the structure-to-performance correlation. Short side chains decorated with N and O atoms as recognition groups were instructed into fluorene to obtain monomers Fmoc-Ala-OH and Fmoc-Thr-OH. Additionally, their polymers and were obtained through electrochemical polymerization. and with high polymerization degrees have an excellent selectivity towards CrO in comparison to other cations and anions. Additionally, their limit of detection could achieve 1.98 fM and 3.72 fM, respectively. Especially, they could realize the trace detection of CrO in agricultural products (red bean, black bean, and millet). All these results indicate that short side chains decorated with N and O atoms functionalizing polyfluorene enables the ultra-trace detection of CrO. Additionally, the design strategy will spark new ideas for the construction of highly selective and sensitive CrO sensors.
鉴于共轭聚合物（CPs）是构建高灵敏度 CrO 传感器的一种有吸引力的选择，但它们缺乏通用的设计策略，我们首先提出了一种合理的 CPs 结构设计，以调整其传感性能，同时验证结构与性能的相关性。用含有 N 和 O 原子的短侧链作为识别基团来修饰芴，得到单体 Fmoc-Ala-OH 和 Fmoc-Thr-OH。此外，通过电化学聚合得到聚合物 和 。具有高聚合度的 和 对 CrO 具有优异的选择性，相对于其他阳离子和阴离子。此外，它们的检测限可以分别达到 1.98 fM 和 3.72 fM。特别是，它们可以实现农产品（红豆、黑豆和小米）中 CrO 的痕量检测。所有这些结果表明，用 N 和 O 原子功能化芴的短侧链可以实现 CrO 的超痕量检测。此外，该设计策略将为构建高选择性和高灵敏度的 CrO 传感器提供新的思路。
