Dong Jinchen, Wang Tangchun, Xu Enze, Bai Feng, Liu Jun, Zhang Zhiliang
State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China.
Faculty of Light Industry, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China.
Nanomaterials (Basel). 2022 Jun 23;12(13):2163. doi: 10.3390/nano12132163.
Considering the inherent hydrophilic and porous nature of paper, the rapid absorption and diffusion of aqueous analyte solutions on paper-based SERS substrates may severely affect the Raman detection sensitivity and accuracy in the detection of target molecules. In this work, a series of hydrophobic CFP@PDA@AuNPs stripes were obtained through in situ synthesizing of gold nanoparticles (AuNPs) on a polydopamine (PDA)-decorated cellulose filter paper (CFP) and functionalized with perfluorodecanethiol (PFDT). When the SERS performance of the substrates was examined using 4-ATP, the hydrophobic CFP@PDA@AuNPs substrate showed superior sensitivity, reproducibility and stability due to the hydrophobic enrichment effect, with the detection limit decreasing to 10 M and the enhancement factor as high as 2.55 × 10. More importantly, it was feasible to apply the hydrophobic paper substrate as an excellent SERS sensor to detect methylene blue (MB) residues in lake water in a highly sensitive manner. The lowest detectable limit of MB was 100 nM, and it showed a low relatively standard deviation (RSD) value of 5.28%. Hydrophobic CFP@PDA@AuNPs stripes may serve as excellent sensors for target molecule detection and have tremendous potential in food security, and environmental and chemical detection.
考虑到纸张固有的亲水性和多孔性，水性分析物溶液在纸基表面增强拉曼散射（SERS）基底上的快速吸收和扩散可能会严重影响目标分子检测中的拉曼检测灵敏度和准确性。在这项工作中，通过在聚多巴胺（PDA）修饰的纤维素滤纸（CFP）上原位合成金纳米颗粒（AuNPs）并使用全氟癸硫醇（PFDT）进行功能化，获得了一系列疏水性CFP@PDA@AuNPs条纹。当使用4-氨基苯硫酚（4-ATP）检测基底的SERS性能时，由于疏水富集效应，疏水性CFP@PDA@AuNPs基底表现出优异的灵敏度、重现性和稳定性，检测限降至10⁻⁸ M，增强因子高达2.55×10⁷。更重要的是，将疏水性纸质基底作为一种优异的SERS传感器以高灵敏度检测湖水中的亚甲基蓝（MB）残留是可行的。MB的最低可检测限为100 nM，并且其相对标准偏差（RSD）值较低，为5.28%。疏水性CFP@PDA@AuNPs条纹可作为目标分子检测的优异传感器，在食品安全、环境和化学检测方面具有巨大潜力。
