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中缝背核神经元在体外的温度敏感性

Thermosensitivity of dorsal raphe neurons in vitro.

作者信息

Keenan C L, Chu N S

出版信息

Brain Res. 1987 Apr 28;410(1):189-94. doi: 10.1016/s0006-8993(87)80045-8.

DOI:10.1016/s0006-8993(87)80045-8
PMID:3580895
Abstract

Thermosensitivity of raphe neurons was studied in tissue slices of rat brainstems (400-500 micron). Measurement of activity of single cells in the dorsal raphe region of the slices revealed that the majority of neurons (89%) were sensitive to changes in temperature. Over the range 34 to 42 degrees C, 3 classes of thermosensitive cells were found: warm (61%), cold (15%) and biphasic type cells (13%). Many dorsal raphe neurons may be intrinsically temperature sensitive and may serve as extrahypothalamic thermodetector components in the integrative process of central thermoregulation.

摘要

在大鼠脑干组织切片(400 - 500微米)中研究了中缝神经元的温度敏感性。对切片中缝背侧区域单个细胞活性的测量显示,大多数神经元(89%)对温度变化敏感。在34至42摄氏度范围内,发现了3类热敏细胞:热敏(61%)、冷敏(15%)和双相型细胞(13%)。许多中缝背侧神经元可能本质上对温度敏感,并且可能在中枢体温调节的整合过程中作为下丘脑外的温度感受器成分。

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Thermosensitivity of dorsal raphe neurons in vitro.中缝背核神经元在体外的温度敏感性
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