Department of Gastrointestinal Surgery, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Department of Gastrointestinal Surgery, Xiangcheng People's Hospital, Suzhou 215006, China.
Cell Mol Biol (Noisy-le-grand). 2022 May 22;68(1):169-176. doi: 10.14715/cmb/2022.68.1.21.
This study aimed to analyze the effects of 5A nursing (including Ask, Assess, Advise, Assist, and Access) combined with psychological nursing on the immune function, cancer-related fatigue, and complications of patients undergoing radical resection of colorectal cancer. For this purpose, 64 patients undergoing radical resection of colorectal cancer were treated with nursing intervention during the perioperative period from March 2019 to March 2021. They were randomly divided into a control group and a study group according to admission order. Each group had 32 cases. The control group performed routine nursing, and 5A nursing combined with psychological nursing was performed on the research group. Then the immune function, cancer-related fatigue, complications, self-efficacy, and nursing satisfaction were compared between the two groups. Results showed that the levels of CD3+ and CD4+ in the two groups were lower than before nursing, and the levels of CD8+, IgA, IgM, and IgG were higher than before nursing (P<0.05). The reduction of CD3+ and CD4+ in the study group was less than the control group, and the increase of CD8+, IgA, IgM, and IgG in the study group was higher than the control group (P<0.05). The scores of cancer-related fatigue after nursing were lower than before nursing (P<0.05), and the reduction of cancer-related fatigue in the study group was higher than the control group (P<0.05). The incidence of postoperative complications in the study group (12.50%) was lower than the control group (25.00%) after nursing (p<0.05). The scores of all dimensions of self-efficacy of the two groups after nursing were higher than before nursing (P<0.05). The improvement of self-efficacy of the study group was better than the control group (P<0.05). The overall nursing satisfaction of the observation group after nursing (96.88%) was higher than the control group (84.38%)(P<0.05). According to the results, the use of 5A nursing combined with psychological nursing can effectively relieve the perioperative psychological pressure of the patients, improve the immune function of the body, relieve cancer-related fatigue, prevent and control the incidence of complications, and improve the quality of clinical life of the patients for patients undergoing radical resection of colorectal cancer.
本研究旨在分析 5A 护理（包括询问、评估、建议、协助和获取）联合心理护理对行直肠癌根治术患者免疫功能、癌因性疲乏及并发症的影响。为此，选取 2019 年 3 月至 2021 年 3 月期间收治的 64 例行直肠癌根治术患者作为研究对象，按照入院顺序分为对照组和观察组，每组 32 例。对照组行常规护理，观察组行 5A 护理联合心理护理。比较两组免疫功能、癌因性疲乏、并发症、自我效能及护理满意度。结果显示，两组护理后 CD3+、CD4+水平均低于护理前，CD8+、IgA、IgM、IgG 水平均高于护理前（P<0.05）；观察组 CD3+、CD4+下降幅度小于对照组，CD8+、IgA、IgM、IgG 升高幅度大于对照组（P<0.05）。护理后两组癌因性疲乏评分均低于护理前（P<0.05），观察组癌因性疲乏评分下降幅度大于对照组（P<0.05）。护理后观察组术后并发症发生率（12.50%）低于对照组（25.00%）（P<0.05）。两组护理后自我效能各维度评分均高于护理前（P<0.05），观察组自我效能改善程度优于对照组（P<0.05）。观察组护理后总满意度（96.88%）高于对照组（84.38%）（P<0.05）。综上所述，5A 护理联合心理护理可有效缓解直肠癌根治术患者围术期心理压力，提高机体免疫功能，缓解癌因性疲乏，预防和控制并发症发生，提高患者临床生活质量。
